Autism spectrum disorder: neuropathology and animal models

M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017‏ - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

Sensory processing in autism: a review of neurophysiologic findings

EJ Marco, LBN Hinkley, SS Hill, SS Nagarajan - Pediatric research, 2011‏ - nature.com
Atypical sensory-based behaviors are a ubiquitous feature of autism spectrum disorders
(ASDs). In this article, we review the neural underpinnings of sensory processing in autism …

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice

A Selimbeyoglu, CK Kim, M Inoue, SY Lee… - Science translational …, 2017‏ - science.org
Alterations in the balance between neuronal excitation and inhibition (E: I balance) have
been implicated in the neural circuit activity–based processes that contribute to autism …

The number of parvalbumin-expressing interneurons is decreased in the prefrontal cortex in autism

E Hashemi, J Ariza, H Rogers, SC Noctor… - Cerebral …, 2017‏ - academic.oup.com
The cognitive phenotype of autism has been correlated with an altered balance of excitation
to inhibition in the cerebral cortex, which could result from a change in the number, function …

In utero exposure to valproic acid and autism—a current review of clinical and animal studies

FI Roullet, JKY Lai, JA Foster - Neurotoxicology and teratology, 2013‏ - Elsevier
Valproic acid (VPA) is both an anti-convulsant and a mood stabilizer. Clinical studies over
the past 40years have shown that exposure to VPA in utero is associated with birth defects …

Social skills deficits in autism spectrum disorder: potential biological origins and progress in develo** therapeutic agents

RE Frye - CNS drugs, 2018‏ - Springer
Autism spectrum disorder is defined by two core symptoms: a deficit in social communication
and the presence of repetitive behaviors and/or restricted interests. Currently, there is no US …

[HTML][HTML] Altered functional and structural brain network organization in autism

JD Rudie, JA Brown, D Beck-Pancer, LM Hernandez… - NeuroImage …, 2013‏ - Elsevier
Structural and functional underconnectivity have been reported for multiple brain regions,
functional systems, and white matter tracts in individuals with autism spectrum disorders …

Sensory symptoms in autism spectrum disorders

EP Hazen, JL Stornelli, JA O'Rourke… - Harvard review of …, 2014‏ - journals.lww.com
The aim of this review is to summarize the recent literature regarding abnormalities in
sensory functioning in individuals with autism spectrum disorder (ASD), including evidence …

Diffusion tensor imaging in autism spectrum disorder: a review

BG Travers, N Adluru, C Ennis, DPM Tromp… - Autism …, 2012‏ - Wiley Online Library
White matter tracts of the brain allow neurons and neuronal networks to communicate and
function with high efficiency. The aim of this review is to briefly introduce diffusion tensor …

[کتاب][B] Sensory perceptual issues in autism and asperger syndrome: different sensory experiences-different perceptual worlds

O Bogdashina - 2016‏ - books.google.com
Completely revised and updated, this book focuses on sensory perceptual problems as
identified by individuals on the autism spectrum. Despite frequently being identified by …