Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Nanodelivery of nucleic acids

BB Mendes, J Conniot, A Avital, D Yao… - Nature reviews …, 2022 - nature.com
There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …

Engineering nanomaterials for glioblastoma nanovaccination

F Hameedat, BB Mendes, J Conniot… - Nature Reviews …, 2024 - nature.com
Glioblastoma is a lethal brain cancer with treatment resistance stemming from its interactions
with the surrounding microenvironment and obstacles such as the blood–brain barrier …

A large-scale machine learning analysis of inorganic nanoparticles in preclinical cancer research

BB Mendes, Z Zhang, J Conniot, DP Sousa… - Nature …, 2024 - nature.com
Owing to their distinct physical and chemical properties, inorganic nanoparticles (NPs) have
shown promising results in preclinical cancer therapy, but designing and engineering them …

Optimized strategies of ROS-based nanodynamic therapies for tumor theranostics

Y Di, R Deng, Z Liu, Y Mao, Y Gao, Q Zhao, S Wang - Biomaterials, 2023 - Elsevier
Reactive oxygen species (ROS) play a crucial role in regulating the metabolism of tumor
growth, metastasis, death and other biological processes. ROS-based nanodynamic …

Extracellular‐vesicle‐based drug delivery systems for enhanced antitumor therapies through modulating the cancer‐immunity cycle

T Yong, Z Wei, L Gan, X Yang - Advanced Materials, 2022 - Wiley Online Library
Although immunotherapy harnessing activity of the immune system against tumors has
made great progress, the treatment efficacy remains limited in most cancers. Current …

Biomimetic ghost nanomedicine-based optotheranostics for cancer

R Prasad, VGS Jyothi, N Kommineni, RT Bulusu… - Nano Letters, 2024 - ACS Publications
Theranostic medicine combines diagnostics and therapeutics, focusing on solid tumors at
minimal doses. Optically activated photosensitizers are significant examples owing to their …

Engineered Bio‐Based Hydrogels for Cancer Immunotherapy

Y Peng, S Liang, QF Meng, D Liu, K Ma… - Advanced …, 2024 - Wiley Online Library
Immunotherapy represents a revolutionary paradigm in cancer management, showcasing its
potential to impede tumor metastasis and recurrence. Nonetheless, challenges including …

Carbon dots as a novel photosensitizer for photodynamic therapy of cancer and bacterial infectious diseases: recent advances

L Sun, Y Zhao, H Peng, J Zhou, Q Zhang, J Yan… - Journal of …, 2024 - Springer
Carbon dots (CDs) are novel carbon-based nanomaterials that have been used as
photosensitizer-mediated photodynamic therapy (PDT) in recent years due to their good …

Application of single-cell sequencing to the research of tumor microenvironment

S Chen, Z Zhou, Y Li, Y Du, G Chen - Frontiers in immunology, 2023 - frontiersin.org
Single-cell sequencing is a technique for detecting and analyzing genomes, transcriptomes,
and epigenomes at the single-cell level, which can detect cellular heterogeneity lost in …