Microsensor systems for cell metabolism are essential tools for investigation and
standardization in cell culture. Electrochemical and optical read-out schemes dominate …

Cell-based therapies have generated great interest in the scientific and medical
communities, and stem cells in particular are very appealing for regenerative medicine, drug …

Therapeutic and industrial applications of pluripotent stem cells and their derivatives require
large cell quantities generated in defined conditions. To this end, we have translated single …

Metabolism is central to embryonic stem cell (ESC) pluripotency and differentiation, with
distinct profiles apparent under different nutrient milieu, and conditions that maintain …

Regenerative medicine relies on harnessing the capacity of stem cells to grow, divide and
differentiate safely and predictably. This may be in the context of expanding stem cells in …

Stem cells always balance between self‐renewal and differentiation. Hence, stem cell
culture parameters are critical and need to be continuously refined according to progress in …

Oxygen plays a pivotal role in cellular homeostasis, and its partial pressure determines
cellular function and fate. Consequently, the ability to control oxygen tension is a critical …

As human pluripotent stem cells (hPSCs) exit pluripotency, they reportedly switch from
glycolytic energy production to primarily mitochondrial metabolism. Here, we show that upon …

Neural progenitor cells (NPCs) derived from pluripotent stem cells (PSCs), including
embryonic stem cells (ESCs) and induced PSCs, are promising cell source for the treatment …

Human and mouse embryonic stem cells (ESCs) exhibit fundamental differences depicting
two distinct states of pluripotency: naive and primed. Mouse ESCs (mESCs) are dependent …