Age-related macular degeneration

P Mitchell, G Liew, B Gopinath, TY Wong - The Lancet, 2018 - thelancet.com
Age-related macular degeneration is a leading cause of visual impairment and severe vision
loss. Clinically, it is classified as early-stage (medium-sized drusen and retinal pigmentary …

[HTML][HTML] Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy

Y Deng, L Qiao, M Du, C Qu, L Wan, J Li, L Huang - Genes & diseases, 2022 - Elsevier
Age-related macular degeneration (AMD) is a complex eye disorder and is the leading
cause of incurable blindness worldwide in the elderly. Clinically, AMD initially affects the …

Refuge challenge: A unified framework for evaluating automated methods for glaucoma assessment from fundus photographs

JI Orlando, H Fu, JB Breda, K Van Keer… - Medical image …, 2020 - Elsevier
Glaucoma is one of the leading causes of irreversible but preventable blindness in working
age populations. Color fundus photography (CFP) is the most cost-effective imaging …

Clinically applicable deep learning for diagnosis and referral in retinal disease

J De Fauw, JR Ledsam, B Romera-Paredes… - Nature medicine, 2018 - nature.com
The volume and complexity of diagnostic imaging is increasing at a pace faster than the
availability of human expertise to interpret it. Artificial intelligence has shown great promise …

[HTML][HTML] Fully automated detection and quantification of macular fluid in OCT using deep learning

T Schlegl, SM Waldstein, H Bogunovic, F Endstraßer… - Ophthalmology, 2018 - Elsevier
Purpose Development and validation of a fully automated method to detect and quantify
macular fluid in conventional OCT images. Design Development of a diagnostic modality …

RETOUCH: The retinal OCT fluid detection and segmentation benchmark and challenge

H Bogunović, F Venhuizen, S Klimscha… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Retinal swelling due to the accumulation of fluid is associated with the most vision-
threatening retinal diseases. Optical coherence tomography (OCT) is the current standard of …

DL-CNN-based approach with image processing techniques for diagnosis of retinal diseases

A Tayal, J Gupta, A Solanki, K Bisht, A Nayyar… - Multimedia …, 2022 - Springer
Artificial intelligence has the potential to revolutionize disease diagnosis, classification, and
identification. However, the implementation of clinical-decision support algorithms for …

Intraoperative imaging in pathology-assisted surgery

FJ Voskuil, J Vonk, B van der Vegt, S Kruijff… - Nature biomedical …, 2022 - nature.com
The pathological assessment of surgical specimens during surgery can reduce the
incidence of positive resection margins, which otherwise can result in additional surgeries or …

Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography

TT Hormel, Y Jia, Y Jian, TS Hwang, ST Bailey… - Progress in Retinal and …, 2021 - Elsevier
Optical coherence tomographic angiography (OCTA) is a novel technology capable of
imaging retinal vasculature three-dimensionally at capillary scale without the need to inject …

[HTML][HTML] AI-based monitoring of retinal fluid in disease activity and under therapy

U Schmidt-Erfurth, GS Reiter, S Riedl… - Progress in retinal and …, 2022 - Elsevier
Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …