Salt sensitivity of blood pressure: a scientific statement from the American Heart Association
F Elijovich, MH Weinberger, CAM Anderson… - …, 2016 - Am Heart Assoc
Hypertension is available at http://hyper. ahajournals. org DOI: 10.1161/HYP.
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …
0000000000000047 e8 Hypertension September 2016 distributed trait. Therefore, defining …
Salt sensitivity and hypertension
O Balafa, RG Kalaitzidis - Journal of human hypertension, 2021 - nature.com
Salt sensitivity refers to the physiological trait present in mammals, including humans, by
which the blood pressure (BP) of some members of the population exhibits changes parallel …
which the blood pressure (BP) of some members of the population exhibits changes parallel …
Hypertension: physiology and pathophysiology
JE Hall, JP Granger, JM do Carmo… - Comprehensive …, 2012 - Wiley Online Library
Despite major advances in understanding the pathophysiology of hypertension and
availability of effective and safe antihypertensive drugs, suboptimal blood pressure (BP) …
availability of effective and safe antihypertensive drugs, suboptimal blood pressure (BP) …
Kidney cadmium toxicity, diabetes and high blood pressure: The Perfect Storm
S Satarug, DA Vesey, GC Gobe - The Tohoku journal of experimental …, 2017 - jstage.jst.go.jp
Cadmium (Cd) is an environmental toxicant of widespread exposure and pervasive toxicity.
Absorption, systemic transport and uptake of Cd are mediated by metal transporters that the …
Absorption, systemic transport and uptake of Cd are mediated by metal transporters that the …
Pathophysiology and genetics of salt-sensitive hypertension
Most hypertensive cases are primary and heavily associated with modifiable risk factors like
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …
20-hydroxyeicosatetraeonic acid: a new target for the treatment of hypertension
JM Williams, S Murphy, M Burke… - Journal of …, 2010 - journals.lww.com
Arachidonic acid is metabolized by enzymes of the CYP4A and 4F families to 20-
hydroxyeicosatetraeonic acid (20-HETE), which plays an important role in the regulation of …
hydroxyeicosatetraeonic acid (20-HETE), which plays an important role in the regulation of …
Functional Variant of CYP4A11 20-Hydroxyeicosatetraenoic Acid Synthase Is Associated With Essential Hypertension
JV Gainer, A Bellamine, EP Dawson, KE Womble… - Circulation, 2005 - Am Heart Assoc
Background—The CYP4A11 arachidonic acid monooxygenase oxidizes endogenous
arachidonic acid (AA) to 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite with …
arachidonic acid (AA) to 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite with …
20-HETE in the regulation of vascular and cardiac function
P Rocic, ML Schwartzman - Pharmacology & therapeutics, 2018 - Elsevier
HETE, the ω-hydroxylation product of arachidonic acid catalyzed by enzymes of the
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …
Genetics of salt-sensitive hypertension
H Sanada, JE Jones, PA Jose - Current hypertension reports, 2011 - Springer
The assessment of salt sensitivity of blood pressure is difficult because of the lack of
universal consensus on definition. Regardless of the variability in the definition of salt …
universal consensus on definition. Regardless of the variability in the definition of salt …
Eicosanoid blood vessel regulation in physiological and pathological states
JD Imig - Clinical Science, 2020 - portlandpress.com
Arachidonic acid can be metabolized in blood vessels by three primary enzymatic pathways;
cyclooxygenase (COX), lipoxygenase (LO), and cytochrome P450 (CYP). These eicosanoid …
cyclooxygenase (COX), lipoxygenase (LO), and cytochrome P450 (CYP). These eicosanoid …