Metabolomics, which is the metabolites profiling in biological matrices, is a key tool for
biomarker discovery and personalized medicine and has great potential to elucidate the …

The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …

Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …

Early diagnosis of neurodegenerative disorders such as Alzheimer's (AD) or Parkinson's
disease (PD) is needed to slow down or halt the disease at the earliest stage. Cerebrospinal …

Human biospecimens are subject to a number of different collection, processing, and
storage factors that can significantly alter their molecular composition and consistency …

Metabolomics, one of the 'omic'sciences in systems biology, is the global assessment and
validation of endogenous small-molecule metabolites within a biologic system. Analysis of …

Background Information regarding the variability of metabolite levels over time in an
individual is required to estimate the reproducibility of metabolite measurements. In …

Metabolomics, the global quantitative assessment of metabolites in a biological system, has
played a pivotal role in various fields of science in the post-genomic era. Metabolites are the …

Introduction The importance of biomarkers for pharmaceutical drug development and clinical
diagnostics is more significant than ever in the current shift toward personalized medicine …

Inflammatory processes involving altered microglial activity may play a relevant role in the
pathophysiology of depressive disorders. Glial fibrillary acidic protein (GFAP) and calcium …