Abstract Coronavirus disease 19 (COVID-19) is a pandemic condition caused by the new
coronavirus SARS-CoV-2. The typical symptoms are fever, cough, shortness of breath …

The intestinal tract is a complex ecosystem that combines resident microbiota and the cells
of various phenotypes with complex metabolic activities that line the epithelial wall. The …

Defensins are small antimicrobial peptides that are produced by leukocytes and epithelial
cells, and that have an important role in innate immunity. Recent advances in understanding …

Neutrophils are the most abundant circulating leucocytes in healthy humans. These cells are
central players during acute inflammatory responses, although a growing body of evidence …

Cardiovascular diseases are a leading cause of mortality and morbidity worldwide.
Neutrophils are a component of the innate immune system which protect against pathogen …

A group of interesting molecules called defensins exhibit multiple functions but have been
primarily recognized to possess a broad spectrum of antimicrobial activities. Studies have …

Host defence peptides (HDPs) are short cationic molecules produced by the immune
systems of most multicellular organisms and play a central role as effector molecules of …

It has been known for many years that the angiotensin-converting enzyme 2 (ACE2) is a cell
surface enzyme involved in the regulation of blood pressure. More recently, it was proven …

Although SARS-CoV-2 is considered a lung-tropic virus that infects the respiratory tract
through binding to the ACE2 cell-surface molecules present on alveolar lungs epithelial …

Neutrophils constitute the first line of defense in human immunity and can be attracted to
inflamed and infected sites by various chemokines. As essential players in immune …