Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Prostate cancer is a major cause of disease and mortality among men, and each year 1.6
million men are diagnosed with and 366,000 men die of prostate cancer. In this review, we …

Importance Obesity, defined as a body mass index (BMI) greater than 30, is associated with
a significant increase in the risk of many cancers and in overall mortality. However, various …

Mutations in PIK3CA, which encodes the p110α subunit of the insulin-activated
phosphatidylinositol-3 kinase (PI3K), and loss of function mutations in PTEN, which encodes …

Cancer is driven by incremental changes that accumulate, eventually leading to oncogenic
transformation. Although genetic alterations dominate the way cancer biologists think about …

Obesity and type 2 diabetes are becoming increasingly prevalent worldwide, and both are
associated with an increased incidence and mortality from many cancers. The metabolic …

Insulin resistance, also known as impaired insulin sensitivity, is the result of a decreased
reaction of insulin signaling to blood glucose levels. This state is observed when muscle …

The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

Answer questions and earn CME/CNE Cancer survivors are often highly motivated to seek
information about food choices, physical activity, and dietary supplements to improve their …

Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …