Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Type 1 diabetes (T1D) is a multifactorial autoimmune disease driven by T-cells against the
insulin-producing islet β-cells, resulting in a marked loss of β-cell mass and function …

For many years, vitamin D has been acknowledged for its role in maintaining calcium and
phosphate balance. However, in recent years, research has assessed its …

The human immune system is highly variable between individuals but relatively stable over
time within a given person. Recent conceptual and technological advances have enabled …

Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes
has grown substantially, particularly with regard to disease prediction and heterogeneity …

The last couple of decades have seen an explosion in our interest and understanding of the
role of vitamin D in the regulation of immunity. At the molecular level, the hormonal form of …

Seasonal variations are rarely considered a contributing component to human tissue
function or health, although many diseases and physiological process display annual …

The pathophysiology of obesity and obesity-related diseases such as type 2 diabetes
mellitus (T2DM) is complex and driven by many factors. One of the most recently identified …

Type 1 diabetes mellitus (T1DM) is the most common autoimmune chronic disease in young
patients. It is caused by the destruction of pancreatic endocrine β-cells that produce insulin …

Objective To assess the risk of new-onset type 1 diabetes mellitus (T1D) diagnosis following
COVID-19 diagnosis and the impact of COVID-19 diagnosis on the risk of diabetic …