Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a
fundamental role in the regulation of bone organogenesis through the activation of receptor …

The hallmark of a stem cell is its ability to self-renew and to produce numerous differentiated
cells. This unique property is controlled by dynamic interplays between extrinsic signalling …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

Elucidating the molecular mechanisms that regulate human stromal (mesenchymal) stem
cell (hMSC) differentiation into osteogenic lineage is important for the development of …

MicroRNAs (miRNAs) interfere with translation of specific target mRNAs and are thought to
thereby regulate many cellular processes. Recent studies have suggested that miRNAs …

e160 Arterioscler Thromb Vasc Biol September 2018 were actively exported to the
cytoplasm with exportin-5 in a Ran-GTP–dependent manner. In the cytoplasm, the transition …

Osteoporosis as a systemic skeletal disorder is characterized by increased bone fragility and
the risk of fractures. According to the World Health Organization, osteoporosis is one of the …

Unicellular marine algae have promise for providing sustainable and scalable biofuel
feedstocks, although no single species has emerged as a preferred organism. Moreover …

Mesenchymal stromal/stem cells (MSCs) are a population of stromal cells present in the
bone marrow and most connective tissues, capable of differentiation into mesenchymal …

Bone is one of the most dynamic organs in the body that continuously undergoes
remodeling through bone formation and resorption. A cascade of molecules and pathways …