The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Background A Task Force was convened by the EFNS/MDS‐ES Scientist Panel on P
arkinson's disease (PD) and other movement disorders to systemically review relevant …

Diffusion-weighted MRI (DW-MRI) has been increasingly used in imaging neuroscience
over the last decade. An early form of this technique, diffusion tensor imaging (DTI) was …

Automatic segmentation of subcortical structures in human brain MR images is an important
but difficult task due to poor and variable intensity contrast. Clear, well-defined intensity …

Background Neuroimaging studies help us better understand the pathophysiology and
symptoms of Parkinson's disease (PD). In several of these studies, diffusion tensor imaging …

Despite advances towards understanding the molecular pathophysiology of the
neurodegenerative dementias, the mechanisms linking molecular changes to …

One objective of modern neuroimaging is to identify markers that can aid in diagnosis,
disease progression monitoring and long-term drug impact analysis. In this study, Parkinson …

Background Development of reliable and accurate imaging biomarkers of dopaminergic cell
neurodegeneration is necessary to facilitate therapeutic drug trials in Parkinson's disease …

Objective: This study assessed whether high-resolution 7 T MRI allowed direct in vivo
visualization of nigrosomes, substructures of the substantia nigra pars compacta (SNpc) …

Objectives: We performed a systematic review to assess alterations in measures of diffusion
tensor imaging (DTI) in parkinsonian syndromes, exploring the potential role of DTI in …