Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

Despite the constant renewal of their components, cellular actin networks maintain their
overall appearance, through a subtle balance of filament assembly and disassembly. This …

Actin filament turnover involves subunits binding to and dissociating from the filament ends,
with the pointed end being the primary site of filament disassembly. Several molecules …

The dynamic turnover of actin filaments drives the morphogenesis and migration of all
eukaryotic cells. This review summarizes recent insights into the molecular mechanisms of …

Cyclase-associated protein (CAP) has emerged as a central player in cellular actin turnover,
but its molecular mechanisms of action are not yet fully understood. Recent studies revealed …

The shape of cells is the outcome of the balance of inner forces produced by the actomyosin
network and the resistive forces produced by cell adhesion to their environment. The specific …

Class I myosins (myosin-Is) colocalize with Arp2/3 complex–nucleated actin networks at
sites of membrane protrusion and invagination, but the mechanisms by which myosin-I …

In cells, multiple actin networks coexist in a dynamic manner. These networks compete for a
common pool of actin monomers and actin-binding proteins. Interestingly, all of these …

While in vitro reconstitution of cellular processes is progressing rapidly, the encapsulation of
biomimetic systems to reproduce the cellular environment is a major challenge. Here we …

Myristoylated, alanine-rich C-kinase substrate (MARCKS) is an F-actin and phospholipid
binding protein implicated in numerous cellular activities, including the regulation of …