Antibody-drug conjugates (ADCs) have emerged as a revolutionary therapeutic class,
combining the precise targeting ability of monoclonal antibodies with the potent cytotoxic …

In spite of the remarkable progress in basic and preclinical studies of acute myeloid
leukemia (AML), the five-year survival rate of AML patients remains poor, highlighting the …

Acute myeloid leukemia (AML) comprises a multifarious and heterogeneous array of
illnesses characterized by the anomalous proliferation of myeloid cells in the bone marrow …

The most critical problem in the treatment of neurodegenerative diseases is brain neuronal
protection, which can be overcome by clearing pathological substances and regulating the …

Neuroinflammation is a pathological hallmark of ALS in both transgenic rodent models and
patients, and is characterized by proinflammatory T lymphocytes and activated …

Since their discovery by Steinman and Cohn in 1973, dendritic cells (DCs) have become
increasingly recognized for their crucial role as regulators of innate and adaptive immunity …

In amyotrophic lateral sclerosis (ALS) mice, regulatory T‐lymphocytes (Tregs) are
neuroprotective, slowing disease progression. To address whether Tregs and FoxP3, a …

Ubiquitination is a post‐translational modification process that has been implicated in the
regulation of innate and adaptive immune responses. There is increasing evidence that both …

Complex regulation of the immune response is necessary to support effective defense of an
organism against hostile invaders and to maintain tolerance to harmless microorganisms …

The microenviroment of acute myelogenous leukemia (AML) is suppressive for immune
effector cells. Regulatory T cells (Tregs) have been recognized as a contributor factor and …