Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

GD de Melo, V Perraud, F Alvarez… - Nature …, 2023 - nature.com
Anosmia was identified as a hallmark of COVID-19 early in the pandemic, however, with the
emergence of variants of concern, the clinical profile induced by SARS-CoV-2 infection has …

Mechanisms of COVID‐19‐associated olfactory dysfunction

K Chang, T Zaikos, N Kilner‐Pontone… - Neuropathology and …, 2024 - Wiley Online Library
Olfactory dysfunction is one of the most common symptoms of COVID‐19. In the first 2 years
of the pandemic, it was frequently reported, although its incidence has significantly …

Longitudinal monitoring of SARS-CoV-2 in wastewater using viral genetic markers and the estimation of unconfirmed COVID-19 cases

L Li, L Mazurowski, A Dewan, M Carine, L Haak… - Science of The Total …, 2022 - Elsevier
In this study, wastewater-based surveillance was carried out to establish the correlation
between SARS-CoV-2 viral RNA concentrations in wastewater and the incidence of corona …

Positive selection underlies repeated knockout of ORF8 in SARS-CoV-2 evolution

C Wagner, KE Kistler, GA Perchetti, N Baker… - Nature …, 2024 - nature.com
Knockout of the ORF8 protein has repeatedly spread through the global viral population
during SARS-CoV-2 evolution. Here we use both regional and global pathogen sequencing …

Evolutionary deletions within the SARS-CoV-2 genome as signature trends for virus fitness and adaptation

PMC Jeronimo, CF Aksenen, IO Duarte… - Journal of …, 2024 - journals.asm.org
Coronaviruses are large RNA viruses that can infect and spread among humans and
animals. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for …

Genomic epidemiology of Delta SARS-CoV-2 during transition from elimination to suppression in Aotearoa New Zealand

L Jelley, J Douglas, X Ren, D Winter, A McNeill… - Nature …, 2022 - nature.com
New Zealand's COVID-19 elimination strategy heavily relied on the use of genomics to
inform contact tracing, linking cases to the border and to clusters during community …

[HTML][HTML] Impairment of antiviral immune response and disruption of cellular functions by SARS-CoV-2 ORF7a and ORF7b

T García-García, R Fernández-Rodríguez, N Redondo… - IScience, 2022 - cell.com
Summary SARS-CoV-2, the causative agent of the present COVID-19 pandemic, possesses
eleven accessory proteins encoded in its genome, and some have been implicated in …

Genome recombination between delta and alpha variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

T Sekizuka, K Itokawa, M Saito, M Shimatani… - MedRxiv, 2021 - medrxiv.org
Prominent genomic recombination has been observed between the Delta and Alpha
variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolated from …

Assessing the transmissibility of the new SARS-CoV-2 variants: from Delta to Omicron

R Dong, T Hu, Y Zhang, Y Li, XH Zhou - Vaccines, 2022 - mdpi.com
Omicron, the latest SARS-CoV-2 Variant of Concern (VOC), first appeared in Africa in
November 2021. At present, the question of whether a new VOC will out-compete the …

SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression

ME McGrath, Y Xue, L Taylor, C Dillen… - PLoS …, 2024 - journals.plos.org
The virus severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, is the causative
agent of the current COVID-19 pandemic. It possesses a large 30 kilobase (kb) genome that …