Deep vein thrombosis (DVT) is a major origin of morbidity and mortality. While DVT has long
been considered as blood coagulation disorder, several recent lines of evidence …

Recently, remarkable developments have taken place, leading to significant improvements
in microfluidic methods to capture subtle biological effects down to single cells. As …

The performance of solid oral dosage forms targeting the colon is typically evaluated using
standardised pharmacopeial dissolution apparatuses. However, these fail to replicate …

Introduction: Venous valves are a type of one-way valves which conduct blood flow toward
the heart and prevent its backflow. Any malfunction of these organs may cause serious …

The proximal part of the colon offers opportunities to prolong the absorption window
following oral administration of a drug. In this work, we used computer simulations to …

Emboli, which are parts of blood clots, can be stuck in the vasculature of various organs
(most frequently, lungs) and cause their malfunction or even death. In this work, using …

Purpose The purpose of this paper is to numerically study the dissolution of solid particles
using the smoothed particle hydrodynamics (SPH) method. Design/methodology/approach …

This paper develops a three-dimensional numerical model for the simulation of cells in
simple shear flow. The model is based on Discrete Multi-Physics (DMP), a meshless particle …

The performance of colon-targeted solid dosage forms is commonly assessed using
standardised pharmacopeial dissolution apparatuses like the USP II or the miniaturised …

This paper demonstrates the use of peridynamics and discrete multiphysics to assess micro
crack formation and propagation in asphalt at low temperatures and under freezing …