The recent acceleration of commercial, private and multi-national spaceflight has created an
unprecedented level of activity in low Earth orbit, concomitant with the largest-ever number …

Human exploration of deep space will involve missions of substantial distance and duration.
To effectively mitigate health hazards, paradigm shifts in astronaut health systems are …

Spaceflight induces an immune response in astronauts. To better characterize this effect, we
generated single-cell, multi-ome, cell-free RNA (cfRNA), biochemical, and hematology data …

Spaceflight induces molecular, cellular and physiological shifts in astronauts and poses
myriad biomedical challenges to the human body, which are becoming increasingly relevant …

Spaceflight can change metabolic, immunological, and biological homeostasis and cause
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …

Anemia in astronauts has been noted since the first space missions, but the mechanisms
contributing to anemia in space flight have remained unclear. Here, we show that space …

Human spaceflight has historically been managed by government agencies, such as in the
NASA Twins Study, but new commercial spaceflight opportunities have opened spaceflight …

Noise is seen as the annoying something for weak signal detection, but noise is beneficial to
enhance weak signals of interest embedded in noise in nonlinear systems. Moreover, the …

Future multi-year crewed planetary missions will motivate advances in aerospace nutrition
and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in …

During spaceflight, the cardiovascular system undergoes remarkable adaptation to
microgravity and faces the risk of cardiac remodeling. Therefore, the effects and …