Huntington disease is a monogenic neurodegenerative disorder that displays an autosomal-
dominant pattern of inheritance. It is characterized by motor, psychiatric, and cognitive …

Huntington's disease (HD) is an inherited autosomal dominant neurodegenerative disorder.
The most prominent sign of HD is the presence of involuntary motor movements. However …

Huntington's disease (HD) is a devastating monogenic neurodegenerative disease
characterized by early, selective pathology in the basal ganglia despite the ubiquitous …

Background TRACK-HD is a multinational prospective observational study of Huntington's
disease (HD) that examines clinical and biological findings of disease progression in …

Huntington's disease (HD) is currently diagnosed based on the presence of motor signs
indicating 99%“diagnostic confidence” for HD. Recent advances in the understanding of HD …

Background Although the association between cytosine-adenine-guanine (CAG) repeat
length and age at onset of Huntington's disease is well known, improved prediction of onset …

Huntington's disease (HD) is traditionally considered as a triad of movement, cognitive, and
emotional disorders. 1–4 According to current clinical practice,“manifest HD” is diagnosed …

RNA-targeting approaches are emerging as viable therapeutics that offer an alternative
method to modulate traditionally 'undrugable'targets. In the case of dominantly inherited …

Cognitive, motor and psychiatric changes in prodromal Huntington's disease have nurtured
the emergent need for early interventions. Preventive clinical trials for Huntington's disease …

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by motor, behavioral, and cognitive manifestations. It is caused by an …