The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Drugs encapsulation is a suitable strategy in order to cope with the limitations of
conventional dosage forms such as unsuitable bioavailability, stability, taste, and odor …

Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …

Background Safe and effective delivery of therapeutic drugs to the brain is important for
successful therapy of Alzheimer's disease (AD). Purpose To develop Huperzine A (HupA) …

In the field of nasal drug delivery, nose-to-brain delivery is among the most fascinating
applications, directly targeting the central nervous system, bypassing the blood brain barrier …

The blood–brain barrier (BBB) plays a fundamental role in protecting the brain from toxic
substances and therefore also controls and restricts the entry of therapeutic agents. The …

The treatment of neurodegenerative and psychiatric disorders remains a challenge in
medical research. Several strategies have been developed over the years, either to …

Epileptic seizures and anxiety crisis are severe conditions that require fast and effective
treatment, targeting the brain. Current emergency antiepiletics and anxiolytics have limited …

While the intranasal administration of drugs to the brain has been gaining both research
attention and regulatory success over the past several years, key fundamental and …