The essential medicinal chemistry of curcumin: miniperspective
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …
Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications
Y Kawabata, K Wada, M Nakatani, S Yamada… - International journal of …, 2011 - Elsevier
The poor oral bioavailability arising from poor aqueous solubility should make drug research
and development more difficult. Various approaches have been developed with a focus on …
and development more difficult. Various approaches have been developed with a focus on …
Wound healing properties of selected natural products
Wound healing is a complex process of recovering the forms and functions of injured
tissues. The process is tightly regulated by multiple growth factors and cytokines released at …
tissues. The process is tightly regulated by multiple growth factors and cytokines released at …
Pharmaceutical strategies of improving oral systemic bioavailability of curcumin for clinical application
Z Ma, N Wang, H He, X Tang - Journal of Controlled Release, 2019 - Elsevier
Curcumin (Cur), a natural compound from Curcuma longa Linn, has various of
pharmacological activities such as anti-cancer, anti-inflammatory, anti-oxidant, anti …
pharmacological activities such as anti-cancer, anti-inflammatory, anti-oxidant, anti …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
Bioavailability of bioactive peptides derived from food proteins across the intestinal epithelial membrane: A review
Abstract Background Bioactive peptides (BAPs) play a crucial physiological role in human
health. To exert their biological effects after oral administration, BAPs have to be transported …
health. To exert their biological effects after oral administration, BAPs have to be transported …
Curcumin's nanomedicine formulations for therapeutic application in neurological diseases
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …
Enhancing the oral bioavailability of curcumin using solid lipid nanoparticles
To control the oral bioavailability of curcumin, we fabricated solid lipid nanoparticles (SLNs)
using tristearin and polyethylene glycol (PEG) ylated emulsifiers. Lipolysis of prepared SLNs …
using tristearin and polyethylene glycol (PEG) ylated emulsifiers. Lipolysis of prepared SLNs …
Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions
H Yu, Q Huang - Journal of agricultural and food chemistry, 2012 - ACS Publications
Curcumin is a natural bioactive compound with many health-promoting benefits. Its low oral
bioavailability limits its application in functional foods. In the present study, novel organogel …
bioavailability limits its application in functional foods. In the present study, novel organogel …
Curcumin, a golden spice with a low bioavailability
A Siviero, E Gallo, V Maggini, L Gori, A Mugelli… - Journal of Herbal …, 2015 - Elsevier
In recent years several drugs have been developed deriving from traditional products and
current drug research is actively investigating the possible therapeutic roles of many …
current drug research is actively investigating the possible therapeutic roles of many …