The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …

Recent evidence has advanced our understanding of the function of sleep to include
removal of neurotoxic protein aggregates via the glymphatic system. However, most …

In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

High-altitude cerebral edema (HACE) and acute mountain sickness (AMS) are
neuropathologies associated with rapid exposure to hypoxia. However, speculation remains …

Diffusion MRI is being used increasingly in studies of the brain and other parts of the body
for its ability to provide quantitative measures that are sensitive to changes in tissue …

The brain exhibits substantial diurnal variation in physiology and function, but neuroscience
studies rarely report or consider the effects of time of day. Here, we examined variation in …

After the introduction of the glymphatic system hypothesis, an increasing number of studies
on cerebrospinal fluid and interstitial fluid dynamics within the brain have been investigated …

The analysis of cerebral perivascular spaces (PVS) using magnetic resonance imaging
(MRI) allows to explore in vivo their contributions to neurological disorders. To date the …

The aim of the present study was to examine cerebrospinal fluid (CSF) volumetric net flow
rate and direction at the cranio-cervical junction (CCJ) and cerebral aqueduct in individuals …