Machine learning in mental health: a sco** review of methods and applications

ABR Shatte, DM Hutchinson, SJ Teague - Psychological medicine, 2019 - cambridge.org
BackgroundThis paper aims to synthesise the literature on machine learning (ML) and big
data applications for mental health, highlighting current research and applications in …

Applications of machine learning algorithms to predict therapeutic outcomes in depression: a meta-analysis and systematic review

Y Lee, RM Ragguett, RB Mansur, JJ Boutilier… - Journal of affective …, 2018 - Elsevier
Background No previous study has comprehensively reviewed the application of machine
learning algorithms in mood disorders populations. Herein, we qualitatively and …

Machine learning in the prediction of depression treatment outcomes: a systematic review and meta-analysis

M Sajjadian, RW Lam, R Milev, S Rotzinger… - Psychological …, 2021 - cambridge.org
Background Multiple treatments are effective for major depressive disorder (MDD), but the
outcomes of each treatment vary broadly among individuals. Accurate prediction of …

Genetic contributions of inflammation to depression

J Barnes, V Mondelli, CM Pariante - Neuropsychopharmacology, 2017 - nature.com
This paper describes the effects of immune genes genetic variants and mRNA expression
on depression's risk, severity, and response to antidepressant treatment, through a …

Low-grade inflammation as a predictor of antidepressant and anti-inflammatory therapy response in MDD patients: a systematic review of the literature in combination …

G Arteaga-Henríquez, MS Simon, B Burger… - Frontiers in …, 2019 - frontiersin.org
Low-grade inflammation plays a role not only in the pathogenesis of major depressive
disorder (MDD) but probably also in the poor responsiveness to regular antidepressants …

Aiding and abetting anhedonia: impact of inflammation on the brain and pharmacological implications

MJ Lucido, M Bekhbat, DR Goldsmith… - Pharmacological …, 2021 - Elsevier
Exogenous administration of inflammatory stimuli to humans and laboratory animals and
chronic endogenous inflammatory states lead to motivational deficits and ultimately …

The emergence, implementation, and future growth of pharmacogenomics in psychiatry: a narrative review

CA Bousman, A Al Maruf, DF Marques… - Psychological …, 2023 - cambridge.org
Psychotropic medication efficacy and tolerability are critical treatment issues faced by
individuals with psychiatric disorders and their healthcare providers. For some people, it can …

Challenges and future prospects of precision medicine in psychiatry

M Manchia, C Pisanu, A Squassina… - Pharmacogenomics …, 2020 - Taylor & Francis
Precision medicine is increasingly recognized as a promising approach to improve disease
treatment, taking into consideration the individual clinical and biological characteristics …

Large-scale transcriptomics studies provide insight into sex differences in depression

ML Seney, J Glausier, E Sibille - Biological psychiatry, 2022 - Elsevier
Major depressive disorder (MDD) is a leading cause of disability, affecting more than 300
million people worldwide. We first review the well-known sex difference in incidence of …

Pharmacogenomics in the treatment of mood disorders: strategies and opportunities for personalized psychiatry

AT Amare, KO Schubert, BT Baune - EPMA journal, 2017 - Springer
Personalized medicine (personalized psychiatry in a specific setting) is a new model
towards individualized care, in which knowledge from genomics and other omic pillars …