Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence

E Christaki, M Marcou, A Tofarides - Journal of molecular evolution, 2020 - Springer
In recent years, we have seen antimicrobial resistance rapidly emerge at a global scale and
spread from one country to the other faster than previously thought. Superbugs and …

Applications of machine learning in human microbiome studies: a review on feature selection, biomarker identification, disease prediction and treatment

LJ Marcos-Zambrano… - Frontiers in …, 2021 - frontiersin.org
The number of microbiome-related studies has notably increased the availability of data on
human microbiome composition and function. These studies provide the essential material …

Effects of early-life antibiotics on the develo** infant gut microbiome and resistome: a randomized trial

M Reyman, MA Van Houten, RL Watson… - Nature …, 2022 - nature.com
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have
pronounced effects on gut microbiome development and selection of antimicrobial …

[HTML][HTML] A global metagenomic map of urban microbiomes and antimicrobial resistance

D Danko, D Bezdan, EE Afshin, S Ahsanuddin… - Cell, 2021 - cell.com
We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60
cities over 3 years, representing the first systematic, worldwide catalog of the urban …

CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database

BP Alcock, AR Raphenya, TTY Lau… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; https://card. mcmaster.
ca) is a curated resource providing reference DNA and protein sequences, detection models …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Antibiotic-resistance genes in waste water

A Karkman, TT Do, F Walsh, MPJ Virta - Trends in microbiology, 2018 - cell.com
Waste water and waste water treatment plants can act as reservoirs and environmental
suppliers of antibiotic resistance. They have also been proposed to be hotspots for …

MEGARes 2.0: a database for classification of antimicrobial drug, biocide and metal resistance determinants in metagenomic sequence data

E Doster, SM Lakin, CJ Dean, C Wolfe… - Nucleic acids …, 2020 - academic.oup.com
Antimicrobial resistance (AMR) is a threat to global public health and the identification of
genetic determinants of AMR is a critical component to epidemiological investigations. High …

Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …

MEGARes and AMR++, v3. 0: an updated comprehensive database of antimicrobial resistance determinants and an improved software pipeline for classification using …

N Bonin, E Doster, H Worley, LJ Pinnell… - Nucleic acids …, 2023 - academic.oup.com
Antimicrobial resistance (AMR) is considered a critical threat to public health, and
genomic/metagenomic investigations featuring high-throughput analysis of sequence data …