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Mitochondrial dynamics in health and disease: mechanisms and potential targets
W Chen, H Zhao, Y Li - Signal transduction and targeted therapy, 2023 - nature.com
Mitochondria are organelles that are able to adjust and respond to different stressors and
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …
Molecular mechanisms of mitochondrial dynamics
Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …
The role of mitochondrial fission in cardiovascular health and disease
JM Quiles, ÅB Gustafsson - Nature Reviews Cardiology, 2022 - nature.com
Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
Mitochondrial dynamics and its involvement in disease
DC Chan - Annual review of pathology: mechanisms of disease, 2020 - annualreviews.org
The dynamic properties of mitochondria—including their fusion, fission, and degradation—
are critical for their optimal function in energy generation. The interplay of fusion and fission …
are critical for their optimal function in energy generation. The interplay of fusion and fission …
Mitochondrial dynamics in health and disease
In animals, mitochondria are mainly organised into an interconnected tubular network
extending across the cell along a cytoskeletal scaffold. Mitochondrial fission and fusion, as …
extending across the cell along a cytoskeletal scaffold. Mitochondrial fission and fusion, as …
Function and regulation of the divisome for mitochondrial fission
Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …
Mitochondrial dynamics: overview of molecular mechanisms
L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
INTRODUCTION There has been an explosion of interest in the role of cell death pathways
and damage-associated molecular pattern (DAMP) signaling in sha** inflammatory and …
and damage-associated molecular pattern (DAMP) signaling in sha** inflammatory and …
Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
Mitochondria sense and respond to many stressors and can support cell survival or death
through energy production and signalling pathways. Mitochondrial responses depend on …
through energy production and signalling pathways. Mitochondrial responses depend on …