Monocyte-mediated defense against microbial pathogens
Circulating blood monocytes supply peripheral tissues with macrophage and dendritic cell
(DC) precursors and, in the setting of infection, also contribute directly to immune defense …
(DC) precursors and, in the setting of infection, also contribute directly to immune defense …
Immune cell subset differentiation and tissue inflammation
P Fang, X Li, J Dai, L Cole, JA Camacho… - Journal of hematology & …, 2018 - Springer
Immune cells were traditionally considered as major pro-inflammatory contributors. Recent
advances in molecular immunology prove that immune cell lineages are composed of …
advances in molecular immunology prove that immune cell lineages are composed of …
Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania
B León, M López-Bravo, C Ardavín - Immunity, 2007 - cell.com
Infection-induced inflammatory reactions involve a strong increase in dendritic cells (DCs) at
the infection site and draining lymph nodes (dLNs). Whether inflammatory DCs are recruited …
the infection site and draining lymph nodes (dLNs). Whether inflammatory DCs are recruited …
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis
M Kohyama, W Ise, BT Edelson, PR Wilker, K Hildner… - Nature, 2009 - nature.com
Tissue macrophages comprise a heterogeneous group of cell types differing in location,
surface markers and function. Red pulp macrophages are a distinct splenic subset involved …
surface markers and function. Red pulp macrophages are a distinct splenic subset involved …
Monocytes give rise to mucosal, but not splenic, conventional dendritic cells
C Varol, L Landsman, DK Fogg… - The Journal of …, 2007 - rupress.org
The mononuclear phagocyte (MP) system is a body-wide macrophage (MΦ) and dendritic
cell (DC) network, which contributes to tissue homeostasis, inflammation, and immune …
cell (DC) network, which contributes to tissue homeostasis, inflammation, and immune …
Cytokine responses against periodontal infection: protective and destructive roles.
YCG Liu, UH Lerner, YTA Teng - Periodontology 2000, 2010 - search.ebscohost.com
The article discusses the protective and destructive roles of cytokine responses against
periodontal infections. It stresses the activities and functions of the protein molecule …
periodontal infections. It stresses the activities and functions of the protein molecule …
Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes
Immediate precursors of the many subtypes of dendritic cells (DCs) remain obscure. Here
we purified a splenic precursor population that produced all splenic CD8+ and CD8 …
we purified a splenic precursor population that produced all splenic CD8+ and CD8 …
Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization
Background Glioblastoma (GBM) may initially respond to treatment with ionizing radiation
(IR), but the prognosis remains extremely poor because the tumors invariably recur. Using …
(IR), but the prognosis remains extremely poor because the tumors invariably recur. Using …
Distinct transcriptional programs control cross-priming in classical and monocyte-derived dendritic cells
Both classical DCs (cDCs) and monocyte-derived DCs (Mo-DCs) are capable of cross-
priming CD8+ T cells in response to cell-associated antigens. We found that Ly-6C hi …
priming CD8+ T cells in response to cell-associated antigens. We found that Ly-6C hi …
Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T‐cell responses
F Geissmann, C Auffray, R Palframan… - Immunology and cell …, 2008 - Wiley Online Library
Monocytes can have important effects on the polarization and expansion of lymphocytes and
may contribute to sha** primary and memory T‐cell responses in humans and mice …
may contribute to sha** primary and memory T‐cell responses in humans and mice …