Monocyte-mediated defense against microbial pathogens

NV Serbina, T Jia, TM Hohl, EG Pamer - Annu. Rev. Immunol., 2008 - annualreviews.org
Circulating blood monocytes supply peripheral tissues with macrophage and dendritic cell
(DC) precursors and, in the setting of infection, also contribute directly to immune defense …

Immune cell subset differentiation and tissue inflammation

P Fang, X Li, J Dai, L Cole, JA Camacho… - Journal of hematology & …, 2018 - Springer
Immune cells were traditionally considered as major pro-inflammatory contributors. Recent
advances in molecular immunology prove that immune cell lineages are composed of …

Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania

B León, M López-Bravo, C Ardavín - Immunity, 2007 - cell.com
Infection-induced inflammatory reactions involve a strong increase in dendritic cells (DCs) at
the infection site and draining lymph nodes (dLNs). Whether inflammatory DCs are recruited …

Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

M Kohyama, W Ise, BT Edelson, PR Wilker, K Hildner… - Nature, 2009 - nature.com
Tissue macrophages comprise a heterogeneous group of cell types differing in location,
surface markers and function. Red pulp macrophages are a distinct splenic subset involved …

Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

C Varol, L Landsman, DK Fogg… - The Journal of …, 2007 - rupress.org
The mononuclear phagocyte (MP) system is a body-wide macrophage (MΦ) and dendritic
cell (DC) network, which contributes to tissue homeostasis, inflammation, and immune …

Cytokine responses against periodontal infection: protective and destructive roles.

YCG Liu, UH Lerner, YTA Teng - Periodontology 2000, 2010 - search.ebscohost.com
The article discusses the protective and destructive roles of cytokine responses against
periodontal infections. It stresses the activities and functions of the protein molecule …

Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes

SH Naik, D Metcalf, A Van Nieuwenhuijze, I Wicks… - Nature …, 2006 - nature.com
Immediate precursors of the many subtypes of dendritic cells (DCs) remain obscure. Here
we purified a splenic precursor population that produced all splenic CD8+ and CD8 …

Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization

JH Stafford, T Hirai, L Deng, SB Chernikova… - Neuro …, 2016 - academic.oup.com
Background Glioblastoma (GBM) may initially respond to treatment with ionizing radiation
(IR), but the prognosis remains extremely poor because the tumors invariably recur. Using …

Distinct transcriptional programs control cross-priming in classical and monocyte-derived dendritic cells

CG Briseño, M Haldar, NM Kretzer, X Wu, DJ Theisen… - Cell reports, 2016 - cell.com
Both classical DCs (cDCs) and monocyte-derived DCs (Mo-DCs) are capable of cross-
priming CD8+ T cells in response to cell-associated antigens. We found that Ly-6C hi …

Blood monocytes: distinct subsets, how they relate to dendritic cells, and their possible roles in the regulation of T‐cell responses

F Geissmann, C Auffray, R Palframan… - Immunology and cell …, 2008 - Wiley Online Library
Monocytes can have important effects on the polarization and expansion of lymphocytes and
may contribute to sha** primary and memory T‐cell responses in humans and mice …