Translational neuroscience bridges insights from specific mechanisms in rodents to complex
functions in humans and is key to advance our general understanding of central nervous …

Learning about threats is crucial for survival and fundamentally rests upon Pavlovian
conditioning. However, Pavlovian threat learning is largely limited to detecting known (or …

Background and objectives Fear conditioning paradigms use various measures to assess
learned fear, including autonomic arousal responses like skin conductance, and self-reports …

Perceived self-efficacy refers to a subject's expectation about the outcomes his/her behavior
will have in a challenging situation. Low self-efficacy has been implicated in the origins and …

Safety behaviors can prevent or minimize a feared outcome. However, in relatively safe
situations, they may be less adaptive, presumably because people will misattribute safety to …

Exposure therapy is widely empirically supported as a treatment for anxiety disorders, but
clinically significant response rates hover around 50%. This study explores strategies for …

The process of learning allows organisms to develop predictions about outcomes in the
environment, and learning is sensitive to both simple associations and higher order …

Exposure-based therapy is an effective treatment for social anxiety, but some patients
relapse. We used a novel virtual reality procedure to examine spontaneous recovery (ie, a …

Background and objectives Pavlovian fear conditioning paradigms are valuable to
investigate fear learning and the return of extinguished fear in the lab. However, their validity …

Overgeneralization of anxiety is a potential etiological factor contributing to anxiety
disorders. Based on perceptual and conceptual generalizations of fear memory, previous …