Effects of heavy metals on fish physiology–a review

M Shahjahan, K Taslima, MS Rahman, M Al-Emran… - Chemosphere, 2022 - Elsevier
The pollution by heavy metals poses a serious threat to the aquatic environment and to the
organisms if the concentration of heavy metals in the environment exceeds the safe limits …

Concise review: MSC-derived exosomes for cell-free therapy

DG Phinney, MF Pittenger - Stem cells, 2017 - academic.oup.com
Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …

Idiopathic pulmonary fibrosis: Disease mechanisms and drug development

P Spagnolo, JA Kropski, MG Jones, JS Lee… - Pharmacology & …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease of unknown cause
characterized by relentless scarring of the lung parenchyma leading to reduced quality of life …

Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing

G Chamberlain, J Fox, B Ashton, J Middleton - Stem cells, 2007 - academic.oup.com
MSCs are nonhematopoietic stromal cells that are capable of differentiating into, and
contribute to the regeneration of, mesenchymal tissues such as bone, cartilage, muscle …

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

K Le Blanc, F Frassoni, L Ball, F Locatelli, H Roelofs… - The Lancet, 2008 - thelancet.com
Background Severe graft-versus-host disease (GVHD) is a life-threatening complication after
allogeneic transplantation with haemopoietic stem cells. Mesenchymal stem cells modulate …

Mechanisms of mesenchymal stem/stromal cell function

JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

MN Islam, SR Das, MT Emin, M Wei, L Sun… - Nature medicine, 2012 - nature.com
Bone marrow–derived stromal cells (BMSCs) protect against acute lung injury (ALI). To
determine the role of BMSC mitochondria in this protection, we airway-instilled mice first with …

Paracrine mechanisms in adult stem cell signaling and therapy

M Gnecchi, Z Zhang, A Ni, VJ Dzau - Circulation research, 2008 - Am Heart Assoc
Animal and preliminary human studies of adult cell therapy following acute myocardial
infarction have shown an overall improvement of cardiac function. Myocardial and vascular …

Idiopathic pulmonary fibrosis

TE King, A Pardo, M Selman - The Lancet, 2011 - thelancet.com
Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …

Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair—current views

DG Phinney, DJ Prockop - Stem cells, 2007 - academic.oup.com
Mesenchymal stem cells or multipotent stromal cells (MSCs) isolated from the bone marrow
of adult organisms were initially characterized as plastic adherent, fibroblastoid cells with the …