Advanced materials and sensors for microphysiological systems: focus on electronic and electrooptical interfaces
Advanced in vitro cell culture systems or microphysiological systems (MPSs), including
microfluidic organ‐on‐a‐chip (OoC), are breakthrough technologies in biomedicine. These …
microfluidic organ‐on‐a‐chip (OoC), are breakthrough technologies in biomedicine. These …
Patient-specific, mechanistic models of tumor growth incorporating artificial intelligence and big data
Despite the remarkable advances in cancer diagnosis, treatment, and management over the
past decade, malignant tumors remain a major public health problem. Further progress in …
past decade, malignant tumors remain a major public health problem. Further progress in …
The synergistic effect of cyclic tensile force and periodontal ligament cell-laden calcium silicate/gelatin methacrylate auxetic hydrogel scaffolds for bone regeneration
The development of 3D printing technologies has allowed us to fabricate complex novel
scaffolds for bone regeneration. In this study, we reported the incorporation of different …
scaffolds for bone regeneration. In this study, we reported the incorporation of different …
Novel Piezoelectric Device for Inducing Strain on Biological Tissue at High Speed
A novel mechanically amplified piezoelectric device is presented that induces large complex
strains on biological tissue at high speeds. This device allows for the mechanotransduction …
strains on biological tissue at high speeds. This device allows for the mechanotransduction …
Design and validation of a modular micro-robotic system for the mechanical characterization of soft tissues
The mechanical properties of tissues are critical design parameters for biomaterials and
regenerative therapies seeking to restore functionality after disease or injury. Characterizing …
regenerative therapies seeking to restore functionality after disease or injury. Characterizing …
In vitro magnetic techniques for investigating cancer progression
Simple Summary This review focuses on the advantages achieved by incorporating
magnetic forces into culture platforms used to study cancer progression in the laboratory …
magnetic forces into culture platforms used to study cancer progression in the laboratory …
Magnetoactive, Kirigami-Inspired Hammocks to Probe Lung Epithelial Cell Function
Introduction Mechanical forces provide critical biological signals to cells. Within the distal
lung, tensile forces act across the basement membrane and epithelial cells atop. Stretching …
lung, tensile forces act across the basement membrane and epithelial cells atop. Stretching …
Remote-controlled 3D porous magnetic interface toward high-throughput dynamic 3D cell culture
Mechanical stimuli have been shown to play a large role in cellular behavior, including
cellular growth, differentiation, morphology, homeostasis, and disease. Therefore …
cellular growth, differentiation, morphology, homeostasis, and disease. Therefore …
Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling
Cancer treatments utilizing biologic or cytotoxic drugs compose the frontline of therapy, and
though gains in treatment efficacy have been persistent in recent decades, much work …
though gains in treatment efficacy have been persistent in recent decades, much work …
High-throughput three-dimensional cellular platforms for screening biophysical microenvironmental signals
Cells in vivo are subjected continuously to multiple biochemical and biophysical stimuli from
their microenvironment that regulate cell fate and function. Although two-dimensional (2D) …
their microenvironment that regulate cell fate and function. Although two-dimensional (2D) …