In patients with HIV-1 infection who are starting combination antiretroviral therapy (ART), the
incidence of immune reconstitution inflammatory syndrome (IRIS) is not well defined. We did …

Two-thirds of the world's HIV-infected people live in sub-Saharan Africa, and more than 1.5
million of them die annually. As access to antiretroviral treatment has expanded within the …

Background Cryptococcus is the most common cause of meningitis in adults living with HIV
in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies …

Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; …

Cryptococcal meningitis causes morbidity and mortality worldwide. The burden of disease is
greatest in middle-and low-income countries with a high incidence of human …

Cryptococcal immune reconstitution inflammatory syndrome (IRIS) may present as a clinical
worsening or new presentation of cryptococcal disease after initiation of antiretroviral …

Individuals with human immunodeficiency virus infection who commence antiretroviral
therapy when they are very immunodeficient are susceptible to immune reconstitution …

Access to antiretroviral therapy (ART) is improving worldwide. Immune reconstitution
inflammatory syndrome (IRIS) is a common complication of ART initiation. In this review, we …

Background Although antiretroviral therapy (ART) improves survival in persons with
cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution …

Background. Cryptococcal meningitis (CM) remains a common AIDS-defining illness in
Africa and Asia. Subclinical cryptococcal antigenemia is frequently unmasked with …