The microbiota and the gut–liver axis in primary sclerosing cholangitis
JR Hov, TH Karlsen - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
Primary sclerosing cholangitis (PSC) offers unique opportunities to explore the gut–liver axis
owing to the close association between liver disease and colonic inflammation. It is well …
owing to the close association between liver disease and colonic inflammation. It is well …
[HTML][HTML] Gut microbiome in primary sclerosing cholangitis: A review
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by
biliary inflammation and stricturing. Exploration of the pathogenesis of PSC in light of its …
biliary inflammation and stricturing. Exploration of the pathogenesis of PSC in light of its …
AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …
[HTML][HTML] Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis
Background & Aims To influence host and disease phenotype, compositional microbiome
changes, which have been demonstrated in patients with primary sclerosing cholangitis …
changes, which have been demonstrated in patients with primary sclerosing cholangitis …
Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis
Q Liu, B Li, Y Li, Y Wei, B Huang, J Liang, Z You, Y Li… - Gut, 2022 - gut.bmj.com
Objective Multiple clinical similarities exist between IgG4-related sclerosing cholangitis
(IgG4-SC) and primary sclerosing cholangitis (PSC), and while gut dysbiosis has been …
(IgG4-SC) and primary sclerosing cholangitis (PSC), and while gut dysbiosis has been …
[HTML][HTML] Nitrate ameliorates dextran sodium sulfate-induced colitis by regulating the homeostasis of the intestinal microbiota
L Hu, L **, D **a, Q Zhang, L Ma, H Zheng, T Xu… - Free Radical Biology …, 2020 - Elsevier
Inflammatory bowel disease (IBD) involves chronic inflammation, loss of epithelial integrity,
and gastrointestinal microbiota dysbiosis. Effective therapies for IBD have not been …
and gastrointestinal microbiota dysbiosis. Effective therapies for IBD have not been …
The intestinal and biliary microbiome in autoimmune liver disease—current evidence and concepts
T Liwinski, M Heinemann, C Schramm - Seminars in Immunopathology, 2022 - Springer
Autoimmune liver diseases are a group of immune-mediated liver diseases with three
distinct entities, including autoimmune hepatitis, primary biliary cholangitis, and primary …
distinct entities, including autoimmune hepatitis, primary biliary cholangitis, and primary …
Current insights on the roles of gut microbiota in inflammatory bowel disease-associated extra-intestinal manifestations: Pathophysiology and therapeutic targets
Y Tie, Y Huang, R Chen, L Li, M Chen, S Zhang - Gut Microbes, 2023 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic, recurrent inflammatory disease of the
gastrointestinal tract. In addition to digestive symptoms, patients with IBD may also develop …
gastrointestinal tract. In addition to digestive symptoms, patients with IBD may also develop …
Primary biliary cholangitis and primary sclerosing cholangitis: current knowledge of pathogenesis and therapeutics
JW Park, JH Kim, SE Kim, JH Jung, MK Jang, SH Park… - Biomedicines, 2022 - mdpi.com
Cholangiopathies encompass various biliary diseases affecting the biliary epithelium,
resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis. Primary biliary …
resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis. Primary biliary …
Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities
M Vesterhus, TH Karlsen - Journal of gastroenterology, 2020 - Springer
Primary sclerosing cholangitis (PSC) is a progressive liver disease, histologically
characterized by inflammation and fibrosis of the bile ducts, and clinically leading to multi …
characterized by inflammation and fibrosis of the bile ducts, and clinically leading to multi …