[HTML][HTML] Implementation and evaluation of an additional GPT-4-based reviewer in PRISMA-based medical systematic literature reviews

A Landschaft, D Antweiler, S Mackay, S Kugler… - International journal of …, 2024 - Elsevier
Background PRISMA-based literature reviews require meticulous scrutiny of extensive
textual data by multiple reviewers, which is associated with considerable human effort …

Matching patients to clinical trials with large language models

Q **, Z Wang, CS Floudas, F Chen, C Gong… - Nature …, 2024 - nature.com
Patient recruitment is challenging for clinical trials. We introduce TrialGPT, an end-to-end
framework for zero-shot patient-to-trial matching with large language models. TrialGPT …

Genegpt: Augmenting large language models with domain tools for improved access to biomedical information

Q **, Y Yang, Q Chen, Z Lu - Bioinformatics, 2024 - academic.oup.com
Motivation While large language models (LLMs) have been successfully applied to various
tasks, they still face challenges with hallucinations. Augmenting LLMs with domain-specific …

Zero-shot clinical trial patient matching with llms

M Wornow, A Lozano, D Dash, J **dal, KW Mahaffey… - NEJM AI, 2025 - ai.nejm.org
Matching patients to clinical trials is a key challenge in bringing new drugs to market.
Identifying patients who meet eligibility criteria for a trial is highly manual, taking up to 1 hour …

Improving retrieval-augmented generation in medicine with iterative follow-up questions

G **ong, Q **, X Wang, M Zhang, Z Lu… - … 2025: Proceedings of …, 2024 - World Scientific
The emergent abilities of large language models (LLMs) have demonstrated great potential
in solving medical questions. They can possess considerable medical knowledge, but may …

[HTML][HTML] A Review of Large Language Models in Healthcare: Taxonomy, Threats, Vulnerabilities, and Framework

R Hamid, S Brohi - Big Data and Cognitive Computing, 2024 - mdpi.com
Due to the widespread acceptance of ChatGPT, implementing large language models
(LLMs) in real-world applications has become an important research area. Such …

A perspective for adapting generalist ai to specialized medical ai applications and their challenges

Z Wang, H Wang, B Danek, Y Li, C Mack… - arxiv preprint arxiv …, 2024 - arxiv.org
The integration of Large Language Models (LLMs) into medical applications has sparked
widespread interest across the healthcare industry, from drug discovery and development to …

End-to-end clinical trial matching with large language models

D Ferber, L Hilgers, IC Wiest, ME Leßmann… - arxiv preprint arxiv …, 2024 - arxiv.org
Matching cancer patients to clinical trials is essential for advancing treatment and patient
care. However, the inconsistent format of medical free text documents and complex trial …

Demystifying large language models for medicine: A primer

Q **, N Wan, R Leaman, S Tian, Z Wang… - arxiv preprint arxiv …, 2024 - arxiv.org
Large language models (LLMs) represent a transformative class of AI tools capable of
revolutionizing various aspects of healthcare by generating human-like responses across …

Criteria2Query 3.0: Leveraging generative large language models for clinical trial eligibility query generation

J Park, Y Fang, C Ta, G Zhang, B Idnay, F Chen… - Journal of Biomedical …, 2024 - Elsevier
Objective Automated identification of eligible patients is a bottleneck of clinical research. We
propose Criteria2Query (C2Q) 3.0, a system that leverages GPT-4 for the semi-automatic …