CD20+ T cells: an emerging T cell subset in human pathology

AYS Lee - Inflammation Research, 2022 - Springer
Introduction Although CD20 is classically a B cell marker, in the last three decades, dim
expression has been noted on a subset of T cells as well that has been independently …

Toward overcoming treatment failure in rheumatoid arthritis

Z Wang, J Huang, D **e, D He, A Lu… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and
bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines …

Efficacy of baricitinib in treating rheumatoid arthritis: Modulatory effects on fibrotic and inflammatory biomarkers in a real-life setting

M d'Alessandro, F Perillo, RM Refini… - International …, 2020 - Elsevier
Background Baricitinib is a JAK inhibitor that blocks intracellular signalling pathways of
inflammatory cytokines recommended for Rheumatoid arthritis (RA) patients not responding …

T cells in ocular autoimmune uveitis: Pathways and therapeutic approaches

M Zhang, X Zhang - International immunopharmacology, 2023 - Elsevier
Autoimmune uveitis is a non-infectious intraocular condition that affects the uveal tract of the
eye and threatens vision if not treated properly. Increasing evidence suggests that activated …

[HTML][HTML] Pharmacogenomics of monoclonal antibodies for the treatment of rheumatoid arthritis

SH Lim, K Kim, CI Choi - Journal of Personalized Medicine, 2022 - mdpi.com
Precision medicine refers to a highly individualized and personalized approach to patient
care. Pharmacogenomics is the study of how an individual's genomic profile affects their …

Involvement of B cells in the development of systemic sclerosis

A Yoshizaki, T Fukasawa, S Ebata… - Frontiers in …, 2022 - frontiersin.org
Systemic sclerosis (SSc) is a rare intractable systemic disease that causes fibrosis and
vasculopathy against a background of autoimmune abnormalities. Although the etiology is …

[HTML][HTML] Rituximab as an adjunctive treatment for schizophrenia spectrum disorder or obsessive-compulsive disorder: Two open-label pilot studies on treatment …

S Bejerot, SS Stein, E Welin, D Eklund, U Hylén… - Journal of Psychiatric …, 2023 - Elsevier
In this explorative study, we investigated if an adjunctive treatment with one single dose of
the monoclonal antibody rituximab would improve symptoms and function in treatment …

B cells in autoimmune hepatitis: bystanders or central players?

C Schultheiß, S Steinmann, AW Lohse… - Seminars in …, 2022 - Springer
B cells are central for the adaptive immune system to mount successful immune responses
not only as antibody producers but also as regulators of cellular immunity. These …

The gene regulatory network controlling plasma cell function

S Trezise, SL Nutt - Immunological Reviews, 2021 - Wiley Online Library
Antibodies are an essential element of the immune response to infection, and in long‐term
protection upon re‐exposure to the same micro‐organism. Antibodies are produced by …

Risk of infections in patients with pemphigus treated with rituximab vs. azathioprine or mycophenolate mofetil: a large-scale global cohort study

K Kridin, N Mruwat, KT Amber… - British Journal of …, 2023 - academic.oup.com
Background The risk of infectious complications among patients with pemphigus managed
by rituximab is yet to be precisely elucidated. Objectives To evaluate the risk of infections in …