Lung ischaemia–reperfusion injury: the role of reactive oxygen species

O Pak, A Sydykov, D Kosanovic, RT Schermuly… - … redox signaling in …, 2017‏ - Springer
Lung ischaemia–reperfusion injury (LIRI) occurs in many lung diseases and during surgical
procedures such as lung transplantation. The re-establishment of blood flow and oxygen …

Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism

K Alhallak, LG Rebello, TJ Muldoon… - Biomedical optics …, 2016‏ - opg.optica.org
The development of prognostic indicators of breast cancer metastatic risk could reduce the
number of patients receiving chemotherapy for tumors with low metastatic potential. Recent …

Evidence of the importance of Nox4 in production of hypertension in Dahl salt-sensitive rats

AW Cowley Jr, C Yang, NN Zheleznova… - …, 2016‏ - ahajournals.org
This study reports the consequences of knocking out NADPH (nicotinamide adenine
dinucleotide phosphate) oxidase 4 (Nox4) on the development of hypertension and kidney …

Hyperspectral imaging fluorescence excitation scanning for colon cancer detection

SJ Leavesley, M Walters, C Lopez… - … of biomedical optics, 2016‏ - spiedigitallibrary.org
Optical spectroscopy and hyperspectral imaging have shown the potential to discriminate
between cancerous and noncancerous tissue with high sensitivity and specificity. However …

Hyperoxia causes mitochondrial fragmentation in pulmonary endothelial cells by increasing expression of pro-fission proteins

C Ma, AM Beyer, M Durand, AV Clough… - … , and vascular biology, 2018‏ - ahajournals.org
Objective—We explored mechanisms that alter mitochondrial structure and function in
pulmonary endothelial cells (PEC) function after hyperoxia. Approach and Results …

Autophagy, TERT, and mitochondrial dysfunction in hyperoxia

AM Beyer, LE Norwood Toro… - American Journal …, 2021‏ - journals.physiology.org
Ventilation with gases containing enhanced fractions of oxygen is the cornerstone of therapy
for patients with hypoxia and acute respiratory distress syndrome. Yet, hyperoxia treatment …

Lipoxin A4 attenuates LPS-induced mouse acute lung injury via Nrf2-mediated E-cadherin expression in airway epithelial cells

X Cheng, S He, J Yuan, S Miao, H Gao, J Zhang… - Free Radical Biology …, 2016‏ - Elsevier
A fundamental element of acute lung injury (ALI) is the inflammation that is part of the body's
immune response to a variety of local or systemic stimuli. Lipoxins (LXs) are important …

Метаболический имиджинг в исследовании онкологических процессов (обзор)

ММ Лукина, МВ Ширманова, ТФ Сергеева… - Современные …, 2016‏ - cyberleninka.ru
Рассмотрены основные подходы к изучению энергетического обмена в опухолевых
клетках, основанные на флюоресцентной визуализации кофакторов НАДН и ФАД …

Ageing‐related changes in GABAergic inhibition in mouse auditory cortex, measured using in vitro flavoprotein autofluorescence imaging

KA Stebbings, HW Choi, A Ravindra… - The Journal of …, 2016‏ - Wiley Online Library
Key points Ageing is associated with hearing loss and changes in GABAergic signalling in
the auditory system. We tested whether GABAergic signalling in an isolated forebrain …