Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …

Microbiomes occupy a range of niches and, in addition to having diverse compositions, they
have varied functional roles that have an impact on agriculture, environmental sciences, and …

We elucidate grapevine evolution and domestication histories with 3525 cultivated and wild
accessions worldwide. In the Pleistocene, harsh climate drove the separation of wild grape …

IscB proteins are putative nucleases encoded in a distinct family of IS200/IS605 transposons
and are likely ancestors of the RNA-guided endonuclease Cas9, but the functions of IscB …

Abstract The Reference Sequence (RefSeq) project at the National Center for Biotechnology
Information (NCBI) provides annotation for over 95 000 prokaryotic genomes that meet …

Background Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal
cord resulting in physical and cognitive impairment in young adults. It is hypothesized that a …

Antibiotic resistance is rapidly spreading via the horizontal transfer of resistance genes in
mobile genetic elements. While plasmids are key drivers of this process, few integrative …

Anaerobic methanotrophic archaea (ANME) carry out anaerobic oxidation of methane, thus
playing a crucial role in the methane cycle. Previous genomic evidence indicates that multi …

Ancient and diverse antibiotic resistance genes (ARGs) have previously been identified from
soil,,, including genes identical to those in human pathogens. Despite the apparent overlap …

T regulatory cells that express the transcription factor Foxp3 (Foxp3+ Tregs) promote tissue
homeostasis in several settings. We now report that symbiotic members of the human gut …