Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

MC Field, D Horn, AH Fairlamb… - Nature Reviews …, 2017 - nature.com
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …

The animal trypanosomiases and their chemotherapy: a review

F Giordani, LJ Morrison, TG Rowan, HP De Koning… - Parasitology, 2016 - cambridge.org
Pathogenic animal trypanosomes affecting livestock have represented a major constraint to
agricultural development in Africa for centuries, and their negative economic impact is …

Trypanosoma evansi and Surra: A Review and Perspectives on Transmission, Epidemiology and Control, Impact, and Zoonotic Aspects

M Desquesnes, A Dargantes, DH Lai… - BioMed research …, 2013 - Wiley Online Library
This paper reviews the transmission modes of Trypanosoma evansi. Its worldwide
distribution is attributed to mechanical transmission. While the role of tabanids is clear, we …

The evolution of trypanosomatid taxonomy

A Kaufer, J Ellis, D Stark, J Barratt - Parasites & vectors, 2017 - Springer
Trypanosomatids are protozoan parasites of the class Kinetoplastida predominately
restricted to invertebrate hosts (ie possess a monoxenous life-cycle). However, several …

Systematic review and meta-analysis on the global distribution, host range, and prevalence of Trypanosoma evansi

WG Aregawi, GE Agga, RD Abdi, P Büscher - Parasites & vectors, 2019 - Springer
Background Surra is an animal trypanosomosis, caused by infection with Trypanosoma
evansi and leading to severe economic loss due to mortality and morbidity. Compared to …

An update on African trypanocide pharmaceutics and resistance

KI Kasozi, ET MacLeod, I Ntulume… - Frontiers in Veterinary …, 2022 - frontiersin.org
African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Tabanids: neglected subjects of research, but important vectors of disease agents!

F Baldacchino, M Desquesnes, S Mihok, LD Foil… - Infection, Genetics and …, 2014 - Elsevier
Tabanids are nuisance pests for people and livestock because of their painful and irritating
bite, persistent biting behavior, and blood ingestion. About 4400 tabanid species have been …

Parasitic diseases of equids in Iran (1931–2020): a literature review

A Sazmand, A Bahari, S Papi, D Otranto - Parasites & vectors, 2020 - Springer
Parasitic infections can cause many respiratory, digestive and other diseases and contribute
to some performance conditions in equids. However, knowledge on the biodiversity of …

Salivarian trypanosomosis: a review of parasites involved, their global distribution and their interaction with the innate and adaptive mammalian host immune system

M Radwanska, N Vereecke, V Deleeuw… - Frontiers in …, 2018 - frontiersin.org
Salivarian trypanosomes are single cell extracellular parasites that cause infections in a
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): bluetongue

EFSA Panel on Animal Health and Welfare … - Efsa …, 2017 - Wiley Online Library
A specific concept of strain was developed in order to classify the BTV serotypes ever
reported in Europe based on their properties of animal health impact: the genotype …