Evaluation of the possible pathways involved in the protective effects of quercetin, naringenin, and rutin at the gene, protein and miRNA levels using in-silico …
Flavonoids are secondary metabolites that are non-essential for plant growth or survival,
and they also provide numerous health benefits to humans. They are antioxidants that shield …
and they also provide numerous health benefits to humans. They are antioxidants that shield …
[HTML][HTML] Metabolite profile, antiproliferative, and antioxidant activity of Acacia auriculiformis and Acacia crassicarpa extracts
Acacia auriculiformis and A. crassicarpa can be used as non-timber forest products to
produce therapeutic agents. To achieve this, it is essential to identify the metabolite profile …
produce therapeutic agents. To achieve this, it is essential to identify the metabolite profile …
Glycine-Conjugated α-Mangostins as Potential Estrogen Receptor Alpha (ERα) Antagonists through Pharmacophore Modeling, Docking Analysis, and Molecular …
Natural compounds have demonstrated good biological activity when combined with certain
amino acids. For example, a glycine-conjugated glycyrrhetinic acid exhibits heightened …
amino acids. For example, a glycine-conjugated glycyrrhetinic acid exhibits heightened …
In silico studies of thiazole derivative towards its potential use against SARS-CoV-2: An intuition from an experimental and computational approach
Abstract The N-(4-methoxyphenyl)-4-phenylthiazole-2-carboxamide (TT7) obtained via
cyclization of methyl 2-((4-methoxyphenyl) amino)-2-oxoethanedithioate with ɑ-haloketone …
cyclization of methyl 2-((4-methoxyphenyl) amino)-2-oxoethanedithioate with ɑ-haloketone …
Discovery of novel VEGFR2-TK inhibitors by phthalimide pharmacophore based virtual screening, molecular docking, MD simulation and DFT
BW Matore, PP Roy, J Singh - Journal of Biomolecular Structure …, 2023 - Taylor & Francis
Currently, numerous potent chemotherapeutic agents are available in the market but most of
them show poor pharmacokinetics, lethal effects and drug resistance during their enduring …
them show poor pharmacokinetics, lethal effects and drug resistance during their enduring …
Evaluation of tamoxifen analogues as potential estrogen receptor alpha inhibitors for breast cancer treatment: A computational approach
A Dashputra, Y Therkar, A Balpande… - Journal of Molecular …, 2024 - Elsevier
Estrogen receptors, particularly ERα, play a key role in breast cancer progression, making
them prime targets for therapeutic intervention. Tamoxifen (TAM), a selective estrogen …
them prime targets for therapeutic intervention. Tamoxifen (TAM), a selective estrogen …
In situ fabrication of Ag nanoparticles modified vertically-grown ZnO nanorods on carbon fiber paper electrode for simultaneous detection of luteolin, daidzein and …
ZH Zhang, YX Zuo, Y Fan, XY Wang, C Wang… - Colloids and Surfaces A …, 2024 - Elsevier
In this paper, a facial strategy is employed to directly growing ZnO nanorods (ZnONR) on
carbon fiber paper (CFP) and functionalizing with silver nanoparticles (AgNP), constructing a …
carbon fiber paper (CFP) and functionalizing with silver nanoparticles (AgNP), constructing a …
Anti-Tuberculosis Potential of OJT008 against Active and Multi-Drug-Resistant Mycobacterium Tuberculosis: In Silico and In Vitro Inhibition of Methionine …
Despite the recent progress in the diagnosis of tuberculosis (TB), the chemotherapeutic
management of TB continues to be challenging. Mycobacterium tuberculosis (Mtb), the …
management of TB continues to be challenging. Mycobacterium tuberculosis (Mtb), the …
Structure elucidation and computational studies of the thiazole derivative against SARS-CoV-2 virus: Insights from XRD, DFT, molecular docking, and molecular …
The present work is focused on the crystal structure, Hirshfeld surface, Density Functional
Theory (DFT) studies of thiazole derivative N-benzyl-4-(4-bromophenyl) thaiazole-2 …
Theory (DFT) studies of thiazole derivative N-benzyl-4-(4-bromophenyl) thaiazole-2 …
Multilayered screening for multi-targeted anti-Alzheimer's and anti-Parkinson's agents through structure-based pharmacophore modelling, MCDM, docking, molecular …
N Chhabra, BW Matore, N Lakra, P Banjare… - In Silico …, 2025 - Springer
Alzheimer's disease (AD) and Parkinson's disease (PD) are neurological conditions that
primarily impact the elderly having distinctive traits and some similarities in terms of …
primarily impact the elderly having distinctive traits and some similarities in terms of …