Current and new frontiers in hereditary cancer surveillance: Opportunities for liquid biopsy

KM Farncombe, D Wong, ML Norman… - The American Journal of …, 2023 - cell.com
At least 5% of cancer diagnoses are attributed to a causal pathogenic or likely pathogenic
germline genetic variant (hereditary cancer syndrome—HCS). These individuals are …

Sharing genetic test results with family members of BRCA, PALB2, CHEK2, and ATM carriers

M Dean, AL Tezak, S Johnson, JK Pierce… - Patient education and …, 2021 - Elsevier
Objective This study explored motivators and challenges/barriers to sharing personal
genetic test results (GTR) with family members (FM). Methods Semi-structured, in-depth …

“How do we rally around the one who was positive?” Familial uncertainty management in the context of men managing BRCA-related cancer risks

EA Rauscher, M Dean, G Campbell-Salome… - Social Science & …, 2019 - Elsevier
Rationale Men with BRCA-related cancer risks face increased disease risk as well as the
prospect of passing on their risk to children. Objective This study investigates men's …

“I am uncertain about what my uncertainty even is”: Men's uncertainty and information management of their BRCA-related cancer risks

EA Rauscher, M Dean… - Journal of Genetic …, 2018 - Springer
Men with a germline pathogenic BRCA1 or BRCA2 variant have increased risks for
develo** breast, pancreatic, prostate, and melanoma cancers, but little is known about …

Patterns of communicating about family health history: exploring differences in family types, age, and sex

G Campbell-Salome, EA Rauscher… - Health Education & …, 2019 - journals.sagepub.com
Family communication environments can be a facilitator or barrier to family cooperation and
communication in collecting family health history (FHH) information, which can facilitate …

“Guys don't have breasts”: the lived experience of men who have BRCA gene mutations and are at risk for male breast cancer

M Skop, J Lorentz, M Jassi… - American journal of …, 2018 - journals.sagepub.com
Men with BRCA1 or BRCA2 gene mutations are at increased risk of develo** breast
cancer and may have an indication for breast cancer screening using mammography. Since …

Psychological Determinants of Men's Adherence to Cascade Screening for BRCA1/2

G Ongaro, S Petrocchi, M Calvello, B Bonanni… - Current …, 2022 - mdpi.com
BRCA1/2 germline mutations predispose carriers to an increased risk of breast, ovarian,
prostate, pancreatic, and skin cancer. Men and women are equally likely to pass on or …

Unmet needs of men with breast cancer

IS Fentiman - European Journal of Surgical Oncology, 2018 - Elsevier
Because of the rarity of male breast cancer (MBC) many men are unaware that the disease
exists. This leads both to delay in presentation and severe distress after diagnosis …

Men's and women's approaches to disclosure about BRCA-related cancer risks and family planning decision-making

M Dean, EA Rauscher - Qualitative health research, 2018 - journals.sagepub.com
Little is known about how men and women who test positive for a BRCA gene mutation or
have a strong family history of carrying a BRCA mutation manage disclosures about their …

Motivation and family communication in hereditary prostate cancer genetic testing: Survey of patients from a US tertiary medical center

CM Finn, S McCormick, D Peterson… - Journal of Genetic …, 2023 - Wiley Online Library
Identification of a hereditary prostate cancer in an affected individual can guide treatment
and may also impact cancer screening and surveillance for patients and their relatives. This …