The human connectome project's neuroimaging approach

MF Glasser, SM Smith, DS Marcus… - Nature …, 2016‏ - nature.com
Noninvasive human neuroimaging has yielded many discoveries about the brain. Numerous
methodological advances have also occurred, though inertia has slowed their adoption. This …

FreeSurfer

B Fischl - Neuroimage, 2012‏ - Elsevier
FreeSurfer is a suite of tools for the analysis of neuroimaging data that provides an array of
algorithms to quantify the functional, connectional and structural properties of the human …

Genetic variants associated with longitudinal changes in brain structure across the lifespan

RM Brouwer, M Klein, KL Grasby, HG Schnack… - Nature …, 2022‏ - nature.com
Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …

[HTML][HTML] SynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retraining

B Billot, DN Greve, O Puonti, A Thielscher… - Medical image …, 2023‏ - Elsevier
Despite advances in data augmentation and transfer learning, convolutional neural
networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans …

OASIS-3: longitudinal neuroimaging, clinical, and cognitive dataset for normal aging and Alzheimer disease

PJ LaMontagne, TLS Benzinger, JC Morris, S Keefe… - medrxiv, 2019‏ - medrxiv.org
ABSTRACT OASIS-3 is a compilation of MRI and PET imaging and related clinical data for
1098 participants who were collected across several ongoing studies in the Washington …

Sleep deprivation impairs molecular clearance from the human brain

PK Eide, V Vinje, AH Pripp, KA Mardal, G Ringstad - Brain, 2021‏ - academic.oup.com
It remains an enigma why human beings spend one-third of their life asleep. Experimental
data suggest that sleep is required for clearance of waste products from brain metabolism …

Robust machine learning segmentation for large-scale analysis of heterogeneous clinical brain MRI datasets

B Billot, C Magdamo, Y Cheng… - Proceedings of the …, 2023‏ - National Acad Sciences
Every year, millions of brain MRI scans are acquired in hospitals, which is a figure
considerably larger than the size of any research dataset. Therefore, the ability to analyze …

[HTML][HTML] Brain-wide glymphatic enhancement and clearance in humans assessed with MRI

G Ringstad, LM Valnes, AM Dale, AH Pripp… - JCI insight, 2018‏ - ncbi.nlm.nih.gov
To what extent does the subarachnoid cerebrospinal fluid (CSF) compartment communicate
directly with the extravascular compartment of human brain tissue? Interconnection between …

Tau positron emission tomographic imaging in aging and early A lzheimer disease

KA Johnson, A Schultz, RA Betensky… - Annals of …, 2016‏ - Wiley Online Library
Objective Detection of focal brain tau deposition during life could greatly facilitate accurate
diagnosis of Alzheimer disease (AD), staging and monitoring of disease progression, and …

The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography

JS Sanchez, JA Becker, HIL Jacobs… - Science translational …, 2021‏ - science.org
Advances in molecular positron emission tomography (PET) have enabled anatomic
tracking of brain pathology in longitudinal studies of normal aging and dementia, including …