Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …

Despite pluripotent stem cells sharing key transcription factors, their maintenance involves
distinct genetic inputs. Emerging evidence suggests that super-enhancers (SEs) can …

Pluripotent stem cells have the potential to generate embryo models that can recapitulate
developmental processes in vitro. Large animals such as pigs may also benefit from stem …

Haplotype‐resolved 3D chromatin architecture related to allelic differences in avian skeletal
muscle development has not been addressed so far, although chicken husbandry for meat …

Embryonic diapause in mammals is a temporary developmental delay occurring at the
blastocyst stage. In contrast to other diapausing species displaying a full arrest, the …

Background The establishment of stable porcine embryonic stem cells (pESCs) can
contribute to basic and biomedical research, including comparative developmental biology …