Metagenome analysis using the Kraken software suite

J Lu, N Rincon, DE Wood, FP Breitwieser… - Nature protocols, 2022 - nature.com
Metagenomic experiments expose the wide range of microscopic organisms in any
microbial environment through high-throughput DNA sequencing. The computational …

Metagenomics: An effective approach for exploring microbial diversity and functions

NN Nam, HDK Do, KT Loan Trinh, NY Lee - Foods, 2023 - mdpi.com
Various fields have been identified in the “omics” era, such as genomics, proteomics,
transcriptomics, metabolomics, phenomics, and metagenomics. Among these …

[HTML][HTML] Comparing the significance of the utilization of next generation and third generation sequencing technologies in microbial metagenomics

I Akacin, Ş Ersoy, O Doluca, M Güngörmüşler - Microbiological Research, 2022 - Elsevier
Since the exploration of sequencing began in 2005, third and next-generation sequencing
(TGS and NGS) technologies have fundamentally changed metagenomics research. These …

The potential role of the microbiota in prostate cancer pathogenesis and treatment

N Pernigoni, C Guo, L Gallagher, W Yuan… - Nature Reviews …, 2023 - nature.com
The human body hosts a complex and dynamic population of trillions of microorganisms—
the microbiota—which influences the body in homeostasis and disease, including cancer …

Unveiling microbial diversity: harnessing long-read sequencing technology

DP Agustinho, Y Fu, VK Menon, GA Metcalf… - Nature …, 2024 - nature.com
Long-read sequencing has recently transformed metagenomics, enhancing strain-level
pathogen characterization, enabling accurate and complete metagenome-assembled …

Evolving approaches to profiling the microbiome in skin disease

Y Chen, R Knight, RL Gallo - Frontiers in Immunology, 2023 - frontiersin.org
Despite its harsh and dry environment, human skin is home to diverse microbes, including
bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may …

Graph-based self-supervised learning for repeat detection in metagenomic assembly

A Azizpour, A Balaji, TJ Treangen, S Segarra - Genome research, 2024 - genome.cshlp.org
Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome
assembly and sequence alignment. This is particularly true for metagenomic data, in which …

Insight into co-hosts of nitrate reduction genes and antibiotic resistance genes in an urban river of the qinghai-tibet plateau

J Hu, Q Chen, S Zhong, Y Liu, Q Gao, EB Graham… - Water Research, 2022 - Elsevier
Microbial co-hosts of nitrate reduction genes (NRGs) and antibiotic resistance genes (ARGs)
have been recently reported, but their ecology and biochemical role in urban waterways …

Inter-kingdom interactions and stability of methanogens revealed by machine-learning guided multi-omics analysis of industrial-scale biogas plants

R Wirth, Z Bagi, P Shetty, M Szuhaj… - The ISME …, 2023 - academic.oup.com
Multi-omics analysis is a powerful tool for the detection and study of inter-kingdom
interactions, such as those between bacterial and archaeal members of complex biogas …

Metagenomic binning with assembly graph embeddings

A Lamurias, M Sereika, M Albertsen, K Hose… - …, 2022 - academic.oup.com
Motivation Despite recent advancements in sequencing technologies and assembly
methods, obtaining high-quality microbial genomes from metagenomic samples is still not a …