Toxicological data bank bridges the gap between environmental risk assessment and green organic chemical design in One Health world
XX Shi, ZZ Wang, XL Sun, YL Wang, HX Liu… - Green …, 2023 - pubs.rsc.org
In the conceptual frame of “One Health”, the safety crisis caused by various toxicological
issues due to chemical exposure is of great concern. The urgent demand for …
issues due to chemical exposure is of great concern. The urgent demand for …
The molecular determinants of pesticide sensitivity in bee pollinators
Bees carry out vital ecosystem services by pollinating both wild and economically important
crop plants. However, while performing this function, bee pollinators may encounter …
crop plants. However, while performing this function, bee pollinators may encounter …
A Locomotor Deficit Induced by Sublethal Doses of Pyrethroid and Neonicotinoid Insecticides in the Honeybee Apis mellifera
M Charreton, A Decourtye, M Henry, G Rodet… - PloS one, 2015 - journals.plos.org
The toxicity of pesticides used in agriculture towards non-targeted organisms and especially
pollinators has recently drawn the attention from a broad scientific community. Increased …
pollinators has recently drawn the attention from a broad scientific community. Increased …
Conservation of the voltage‐sensitive sodium channel protein within the Insecta
JJ Silva, JG Scott - Insect molecular biology, 2020 - Wiley Online Library
The voltage‐sensitive sodium channel (VSSC) is essential for the generation and
propagation of action potentials. VSSC kinetics can be modified by producing different splice …
propagation of action potentials. VSSC kinetics can be modified by producing different splice …
Eukaryotic voltage-gated sodium channels: on their origins, asymmetries, losses, diversification and adaptations
JE Fux, A Mehta, J Moffat, JD Spafford - Frontiers in Physiology, 2018 - frontiersin.org
The appearance of voltage-gated, sodium-selective channels with rapid gating kinetics was
a limiting factor in the evolution of nervous systems. Two rounds of domain duplications …
a limiting factor in the evolution of nervous systems. Two rounds of domain duplications …
Molecular basis of selective resistance of the bumblebee BiNav1 sodium channel to tau-fluvalinate
S Wu, Y Nomura, Y Du, BS Zhorov… - Proceedings of the …, 2017 - National Acad Sciences
Insecticides are widely used to control pests in agriculture and insect vectors that transmit
human diseases. However, these chemicals can have a negative effect on nontarget …
human diseases. However, these chemicals can have a negative effect on nontarget …
Honey bees long-lasting locomotor deficits after exposure to the diamide chlorantraniliprole are accompanied by brain and muscular calcium channels alterations
A Kadala, M Charreton, P Charnet, C Collet - Scientific Reports, 2019 - nature.com
Diamides belong to one of the newest insecticides class. We characterized cellular effects of
the first commercialized diamide, chlorantraniliprole (ChlorAnt). ChlorAnt not only induces a …
the first commercialized diamide, chlorantraniliprole (ChlorAnt). ChlorAnt not only induces a …
Pyrethroids in an AlphaFold2 model of the insect sodium channel
BS Zhorov, K Dong - Insects, 2022 - mdpi.com
Simple Summary Pyrethroids are a major class of insecticides for controlling arthropod pests
and human disease transmitting vectors. Resistance to pyrethroid insecticides presents a …
and human disease transmitting vectors. Resistance to pyrethroid insecticides presents a …
[HTML][HTML] Unravelling impacts of the insecticide deltamethrin on neuronal sodium channels in honey bees: Molecular insights and behavioural outcomes
A Kadala, M Kaabeche, M Charreton, J Mutterer… - Chemosphere, 2024 - Elsevier
The current risk assessment framework for insecticides suffers from certain shortcomings in
adequately addressing the effects of low doses on off-target species. To remedy this gap, a …
adequately addressing the effects of low doses on off-target species. To remedy this gap, a …
Cardiotoxicity of the diamide insecticide chlorantraniliprole in the intact heart and in isolated cardiomyocytes from the honey bee
M Kaabeche, M Charreton, A Kadala, J Mutterer… - Scientific Reports, 2024 - nature.com
In honey bees, circulation of blood (hemolymph) is driven by the peristaltic contraction of the
heart vessel located in the dorsal part of the abdomen. Chlorantraniliprole (CHL) is an …
heart vessel located in the dorsal part of the abdomen. Chlorantraniliprole (CHL) is an …