Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Hydrogels in spinal cord injury repair: a review

Z Lv, C Dong, T Zhang, S Zhang - Frontiers in bioengineering and …, 2022 - frontiersin.org
Traffic accidents and falling objects are responsible for most spinal cord injuries (SCIs). SCI
is characterized by high disability and tends to occur among the young, seriously affecting …

Defining and designing polymers and hydrogels for neural tissue engineering

ER Aurand, KJ Lampe, KB Bjugstad - Neuroscience research, 2012 - Elsevier
The use of biomaterials, such as hydrogels, as neural cell delivery devices is becoming
more common in areas of research such as stroke, traumatic brain injury, and spinal cord …

PEDOT and PEDOT: PSS conducting polymeric hydrogels: A report on their emerging applications

MA Bhat, RA Rather, AH Shalla - Synthetic Metals, 2021 - Elsevier
Conducting polymers (CP's) are currently being explored in areas like bio-interfaces,
bioelectronics and medical purposes. Inclusion of moieties of CP's into hydrogels has …

Properties of as-prepared and freeze-dried hydrogels made from poly (vinyl alcohol) and cellulose nanocrystals using freeze-thaw technique

S Butylina, S Geng, K Oksman - European Polymer Journal, 2016 - Elsevier
Poly (vinyl alcohol), PVA hydrogels are potential materials for biomedical and
biotechnogical applications. However, their low mechanical properties restrict their use. In …

3D bioprinting approaches for spinal cord injury repair

J Jiu, H Liu, D Li, J Li, L Liu, W Yang, L Yan, S Li… - …, 2024 - iopscience.iop.org
Regenerative healing of spinal cord injury (SCI) poses an ongoing medical challenge by
causing persistent neurological impairment and a significant socioeconomic burden. The …

Differentiation of neuronal stem cells into motor neurons using electrospun poly-L-lactic acid/gelatin scaffold

L Binan, C Tendey, G De Crescenzo, R El Ayoubi… - Biomaterials, 2014 - Elsevier
Neural stem cells (NSCs) provide promising therapeutic potential for cell replacement
therapy in spinal cord injury (SCI). However, high increases of cell viability and poor control …

A conductive dual-network hydrogel composed of oxidized dextran and hyaluronic-hydrazide as BDNF delivery systems for potential spinal cord injury repair

F Huang, T Chen, J Chang, C Zhang, F Liao… - International Journal of …, 2021 - Elsevier
Spinal cord injury (SCI) often causes neuronal death and axonal degeneration. In this study,
we report a new strategy for preparing injectable and conductive polysaccharides-based …