Antibiotic allergy
Antibiotics are the commonest cause of life-threatening immune-mediated drug reactions
that are considered off-target, including anaphylaxis, and organ-specific and severe …
that are considered off-target, including anaphylaxis, and organ-specific and severe …
The challenge of de‐labeling penicillin allergy
Abstract Background Even though 8%‐25% of most populations studied globally are labeled
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …
as penicillin allergic, most diagnoses of penicillin allergy are made in childhood and relate …
Risk of meticillin resistant Staphylococcus aureus and Clostridium difficile in patients with a documented penicillin allergy: population based matched cohort study
Objective To evaluate the relation between penicillin allergy and development of meticillin
resistant Staphylococcus aureus (MRSA) and C difficile. Design Population based matched …
resistant Staphylococcus aureus (MRSA) and C difficile. Design Population based matched …
[HTML][HTML] Tackling inpatient penicillin allergies: assessing tools for antimicrobial stewardship
Background Reported penicillin allergy rarely reflects penicillin intolerance. Failure to
address inpatient penicillin allergies results in more broad-spectrum antibiotic use, treatment …
address inpatient penicillin allergies results in more broad-spectrum antibiotic use, treatment …
[HTML][HTML] The cost of self-reported penicillin allergy: a systematic review
TJ Mattingly II, A Fulton, RA Lumish… - The Journal of Allergy …, 2018 - Elsevier
Background Patients who report a penicillin (PCN) allergy receive suboptimal antibiotic
therapy compared with patients not reporting an allergy. However, a majority of patients who …
therapy compared with patients not reporting an allergy. However, a majority of patients who …
Impact of an integrated antibiotic allergy testing program on antimicrobial stewardship: a multicenter evaluation
Background Despite the high prevalence of patient-reported antibiotic allergy (so-called
antibiotic allergy labels [AALs]) and their impact on antibiotic prescribing, incorporation of …
antibiotic allergy labels [AALs]) and their impact on antibiotic prescribing, incorporation of …
Penicillin allergy testing is cost-saving: an economic evaluation study
Background Having a penicillin allergy label is associated with the use of less appropriate
and more expensive antibiotics and increased healthcare utilization. Penicillin allergy …
and more expensive antibiotics and increased healthcare utilization. Penicillin allergy …
The impact of reported beta-lactam allergy in hospitalized patients with hematologic malignancies requiring antibiotics
KHG Huang, V Cluzet, K Hamilton… - Clinical Infectious …, 2018 - academic.oup.com
Background Patients hospitalized with hematologic malignancy are particularly vulnerable
to infection. The impact of reported beta-lactam (BL) allergy in this population remains …
to infection. The impact of reported beta-lactam (BL) allergy in this population remains …
The 3 Cs of antibiotic allergy—classification, cross-reactivity, and collaboration
Antibiotic allergy labeling is highly prevalent and negatively impacts patient outcomes and
antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies …
antibiotic appropriateness. Reducing the prevalence and burden of antibiotic allergies …
Antibiotic allergy labels in children are associated with adverse clinical outcomes
M Lucas, A Arnold, A Sommerfield, M Trevenen… - The Journal of Allergy …, 2019 - Elsevier
Background Self-reported antibiotic allergies are common among hospitalized adults and
children. However, there is a paucity of studies investigating the impact of an antibiotic …
children. However, there is a paucity of studies investigating the impact of an antibiotic …