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Thyroid-disrupting chemicals and brain development: an update
This review covers recent findings on the main categories of thyroid hormone–disrupting
chemicals and their effects on brain development. We draw mostly on epidemiological and …
chemicals and their effects on brain development. We draw mostly on epidemiological and …
Insufficiency of thyroid hormone in frog metamorphosis and the role of glucocorticoids
LM Sachs, DR Buchholz - Frontiers in Endocrinology, 2019 - frontiersin.org
Thyroid hormone (TH) is the most important hormone in frog metamorphosis, a
developmental process which will not occur in the absence of TH but can be induced …
developmental process which will not occur in the absence of TH but can be induced …
Thyroid hormone links environmental signals to DNA methylation
Environmental conditions experienced within and across generations can impact individual
phenotypes via so-called 'epigenetic'processes. Here we suggest that endocrine signalling …
phenotypes via so-called 'epigenetic'processes. Here we suggest that endocrine signalling …
DNA methylation in autoimmune thyroid disease
N Lafontaine, SG Wilson… - The Journal of Clinical …, 2023 - academic.oup.com
Graves disease and Hashimoto disease form part of the spectrum of autoimmune thyroid
disease (AITD), to which genetic and environmental factors are recognized contributors …
disease (AITD), to which genetic and environmental factors are recognized contributors …
DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging
To address how conserved DNA methylation-based epigenetic aging is in diverse branches
of the tree of life, we generated DNA methylation data from African clawed frogs (Xenopus …
of the tree of life, we generated DNA methylation data from African clawed frogs (Xenopus …
Novel insight into the epigenetic and post-transcriptional control of cardiac gene expression by thyroid hormone
Thyroid hormone (TH) signaling is critically involved in the regulation of cardiovascular
physiology. Even mild reductions of myocardial TH levels, as occur in hypothyroidism or low …
physiology. Even mild reductions of myocardial TH levels, as occur in hypothyroidism or low …
Thyroid Hormone Induces DNA Demethylation in Xenopus Tadpole Brain
Thyroid hormone (T3) plays pivotal roles in vertebrate development, acting via nuclear T3
receptors (TRs) that regulate gene transcription by promoting post-translational …
receptors (TRs) that regulate gene transcription by promoting post-translational …
Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9
A Weihs, L Chaker, TC Martin, KVE Braun… - Thyroid, 2023 - liebertpub.com
Background: Thyroid hormones play a key role in differentiation and metabolism and are
known regulators of gene expression through both genomic and epigenetic processes …
known regulators of gene expression through both genomic and epigenetic processes …
Follicular Thyroid Adenoma and Follicular Thyroid Carcinoma—A Common or Distinct Background? Loss of Heterozygosity in Comprehensive Microarray Study
Simple Summary Approximately 50% of 60-year-old persons have thyroid nodules that in 7–
15% may be thyroid cancer. Diagnosis of follicular thyroid adenoma (FTA) and follicular …
15% may be thyroid cancer. Diagnosis of follicular thyroid adenoma (FTA) and follicular …
[HTML][HTML] Transcriptome and methylome analysis reveal complex cross-talks between thyroid hormone and glucocorticoid signaling at xenopus metamorphosis
Background: Most work in endocrinology focus on the action of a single hormone, and very
little on the cross-talks between two hormones. Here we characterize the nature of …
little on the cross-talks between two hormones. Here we characterize the nature of …