Thyroid-disrupting chemicals and brain development: an update

BB Mughal, JB Fini, BA Demeneix - Endocrine connections, 2018 - ec.bioscientifica.com
This review covers recent findings on the main categories of thyroid hormone–disrupting
chemicals and their effects on brain development. We draw mostly on epidemiological and …

Insufficiency of thyroid hormone in frog metamorphosis and the role of glucocorticoids

LM Sachs, DR Buchholz - Frontiers in Endocrinology, 2019 - frontiersin.org
Thyroid hormone (TH) is the most important hormone in frog metamorphosis, a
developmental process which will not occur in the absence of TH but can be induced …

Thyroid hormone links environmental signals to DNA methylation

F Seebacher, AG Little - Philosophical Transactions of …, 2024 - royalsocietypublishing.org
Environmental conditions experienced within and across generations can impact individual
phenotypes via so-called 'epigenetic'processes. Here we suggest that endocrine signalling …

DNA methylation in autoimmune thyroid disease

N Lafontaine, SG Wilson… - The Journal of Clinical …, 2023 - academic.oup.com
Graves disease and Hashimoto disease form part of the spectrum of autoimmune thyroid
disease (AITD), to which genetic and environmental factors are recognized contributors …

DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging

JA Zoller, E Parasyraki, AT Lu, A Haghani, C Niehrs… - GeroScience, 2024 - Springer
To address how conserved DNA methylation-based epigenetic aging is in diverse branches
of the tree of life, we generated DNA methylation data from African clawed frogs (Xenopus …

Novel insight into the epigenetic and post-transcriptional control of cardiac gene expression by thyroid hormone

F Forini, G Nicolini, L Pitto, G Iervasi - Frontiers in Endocrinology, 2019 - frontiersin.org
Thyroid hormone (TH) signaling is critically involved in the regulation of cardiovascular
physiology. Even mild reductions of myocardial TH levels, as occur in hypothyroidism or low …

Thyroid Hormone Induces DNA Demethylation in Xenopus Tadpole Brain

S Raj, Y Kyono, CJ Sifuentes… - …, 2020 - academic.oup.com
Thyroid hormone (T3) plays pivotal roles in vertebrate development, acting via nuclear T3
receptors (TRs) that regulate gene transcription by promoting post-translational …

Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9

A Weihs, L Chaker, TC Martin, KVE Braun… - Thyroid, 2023 - liebertpub.com
Background: Thyroid hormones play a key role in differentiation and metabolism and are
known regulators of gene expression through both genomic and epigenetic processes …

Follicular Thyroid Adenoma and Follicular Thyroid Carcinoma—A Common or Distinct Background? Loss of Heterozygosity in Comprehensive Microarray Study

M Borowczyk, P Dobosz, E Szczepanek-Parulska… - Cancers, 2023 - mdpi.com
Simple Summary Approximately 50% of 60-year-old persons have thyroid nodules that in 7–
15% may be thyroid cancer. Diagnosis of follicular thyroid adenoma (FTA) and follicular …

[HTML][HTML] Transcriptome and methylome analysis reveal complex cross-talks between thyroid hormone and glucocorticoid signaling at xenopus metamorphosis

N Buisine, A Grimaldi, V Jonchere, M Rigolet… - Cells, 2021 - mdpi.com
Background: Most work in endocrinology focus on the action of a single hormone, and very
little on the cross-talks between two hormones. Here we characterize the nature of …