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Horizontal gene transfer of antibiotic resistance genes in biofilms
C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …
Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …
Mobile genetic element flexibility as an underlying principle to bacterial evolution
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …
ecosystem health. Here, we use a framework of a hierarchical and modular system that …
[HTML][HTML] ARGs-OAP v3. 0: Antibiotic-resistance gene database curation and analysis pipeline optimization
Antibiotic resistance, which is encoded by antibiotic-resistance genes (ARGs), has
proliferated to become a growing threat to public health around the world. With technical …
proliferated to become a growing threat to public health around the world. With technical …
mobileOG-db: a manually curated database of protein families mediating the life cycle of bacterial mobile genetic elements
Bacterial mobile genetic elements (MGEs) encode functional modules that perform both core
and accessory functions for the element, the latter of which are often only transiently …
and accessory functions for the element, the latter of which are often only transiently …
Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids
C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …
the plasmids encode the functions necessary to conjugate autonomously, the others being …
Evidence for wastewaters as environments where mobile antibiotic resistance genes emerge
The emergence and spread of mobile antibiotic resistance genes (ARGs) in pathogens have
become a serious threat to global health. Still little is known about where ARGs gain mobility …
become a serious threat to global health. Still little is known about where ARGs gain mobility …
Mating pair stabilization mediates bacterial conjugation species specificity
Bacterial conjugation mediates contact-dependent transfer of DNA from donor to recipient
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …
Phage-plasmids spread antibiotic resistance genes through infection and lysogenic conversion
Antibiotic resistance is rapidly spreading via the horizontal transfer of resistance genes in
mobile genetic elements. While plasmids are key drivers of this process, few integrative …
mobile genetic elements. While plasmids are key drivers of this process, few integrative …
VRprofile2: detection of antibiotic resistance-associated mobilome in bacterial pathogens
M Wang, YX Goh, C Tai, H Wang, Z Deng… - Nucleic acids …, 2022 - academic.oup.com
VRprofile2 is an updated pipeline that rapidly identifies diverse mobile genetic elements in
bacterial genome sequences. Compared with the previous version, three major …
bacterial genome sequences. Compared with the previous version, three major …