Alzheimer's disease (AD) is the most common type of dementia in the elderly. Several
hypotheses emerged from AD pathophysiological mechanisms. However, no neuronal …

Alzheimer is an irreversible progressive neurodegenerative disease that causes failure of
cerebral neurons and disability of the affected person to practice normal daily life activities …

Neuroplasticity refers to the ability of brain circuits to reorganize and change the properties
of the network, resulting in alterations in brain function and behavior. It is traditionally …

Early childhood serves as a critical period for neural development and skill acquisition when
children are extremely susceptible to the external environment and experience. As a crucial …

Synaptic plasticity constitutes a fundamental process in the reorganization of neural
networks that underlie memory, cognition, emotional responses, and behavioral planning. At …

The formation of the human gut microbiome initiates in utero, and its maturation is
established during the first 2–3 years of life. Numerous factors alter the composition of the …

Serotonergic neurons constitute one of the main systems of neuromodulators, whose diffuse
projections regulate the functions of the cerebral cortex. Serotonin (5-HT) is known to play a …

Abstract Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are commonly prescribed to
women during pregnancy and breastfeeding despite posing a risk of adverse cognitive …

Summary Serotonin (5-HT) modulates early development during critical periods when
experience drives heightened levels of plasticity in neurons. Here, we investigate the …

The optimization of brain circuit connectivity based on initial environmental input occurs
during critical periods characterized by sensory experience-dependent, temporally …