S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles

R Donato - The international journal of biochemistry & cell biology, 2001 - Elsevier
S100 is a multigenic family of non-ubiquitous Ca2+-modulated proteins of the EF-hand type
expressed in vertebrates exclusively and implicated in intracellular and extracellular …

S100B in brain damage and neurodegeneration

M Rothermundt, M Peters, JHM Prehn… - … research and technique, 2003 - Wiley Online Library
S100B is a calcium‐binding peptide produced mainly by astrocytes that exert paracrine and
autocrine effects on neurons and glia. Some knowledge has been acquired from in vitro and …

[HTML][HTML] Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

HJ Huttunen, J Kuja-Panula, G Sorci… - Journal of Biological …, 2000 - Elsevier
Amphoterin is a protein enhancing process extension and migration in embryonic neurons
and in tumor cells through binding to receptor for advanced glycation end products (RAGE) …

The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain

LJ Van Eldik, MS Wainwright - Restorative neurology and …, 2003 - content.iospress.com
Glia play active and vital roles in the CNS, including regulation of brain development,
maintenance of cellular homeostasis and reparative responses to acute and chronic …

Biological and methodological features of the measurement of S100B, a putative marker of brain injury

CA Gonçalves, MC Leite, P Nardin - Clinical biochemistry, 2008 - Elsevier
The S100B astroglial protein is widely used as a parameter of glial activation and/or death in
several conditions of brain injury. Cerebrospinal fluid and serum S100B variations have …

S100B in neuropathologic states: the CRP of the brain?

J Sen, A Belli - Journal of neuroscience research, 2007 - Wiley Online Library
In recent years there has been a proliferation of interest in the brain‐specific protein S100B,
its many physiologic roles, and its behaviour in various neuropathologic conditions. Since …

Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1β production

SH Kim, CJ Smith, LJ Van Eldik - Neurobiology of aging, 2004 - Elsevier
In Alzheimer's disease (AD), chronically activated glia contribute to neuronal dysfunction
through production of neuroinflammatory molecules like interleukin (IL)-1β. As a first step to …

Enhanced hippocampal neurogenesis by intraventricular S100B infusion is associated with improved cognitive recovery after traumatic brain injury

A Kleindienst, MJ McGinn, HB Harvey… - Journal of …, 2005 - liebertpub.com
Evidence of injury-induced neurogenesis in the adult hippocampus suggests that an
endogenous repair mechanism exists for cognitive dysfunction following traumatic brain …

A critical analysis of the role of the neurotrophic protein S100B in acute brain injury

A Kleindienst, MR Bullock - Journal of neurotrauma, 2006 - liebertpub.com
We provide a critical analysis of the relevance of S100B in acute brain injury emphazising
the beneficial effect of its biological properties. S100B is a calcium-binding protein, primarily …

Oxidative modifications of S100 proteins: functional regulation by redox

SY Lim, MJ Raftery, J Goyette, K Hsu… - Journal of leukocyte …, 2009 - academic.oup.com
Alterations in the capability of CF lung macrophage to respond and clear airway pathogens
might contribute to the development of lung disease in cystic fibrosis. Several S100 Ca2+ …