Recombinase-mediated cassette exchange (RMCE)—a rapidly-expanding toolbox for targeted genomic modifications

S Turan, C Zehe, J Kuehle, J Qiao, J Bode - Gene, 2013 - Elsevier
Starting in 1991, the advance of Tyr-recombinases Flp and Cre enabled superior strategies
for the predictable insertion of transgenes into compatible target sites of mammalian cells …

Cell-specific translational profiling in acute kidney injury

J Liu, AM Krautzberger, SH Sui… - The Journal of …, 2014 - Am Soc Clin Investig
Acute kidney injury (AKI) promotes an abrupt loss of kidney function that results in
substantial morbidity and mortality. Considerable effort has gone toward identification of …

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

KA Peterson, Y Nishi, W Ma, A Vedenko… - Genes & …, 2012 - genesdev.cshlp.org
In the vertebrate neural tube, regional Sonic hedgehog (Shh) signaling invokes a time-and
concentration-dependent induction of six different cell populations mediated through Gli …

[HTML][HTML] Embryonic stem cells: a perfect tool for studying mammalian transcriptional enhancers

S Rao - Journal of stem cell research & therapy, 2012 - ncbi.nlm.nih.gov
Transcriptional enhancers are DNA elements capable of regulating gene expression in-cis
over great distances. With the recent availability of genomic approaches to define epigenetic …

Recombinase technology for precise genome engineering

JG Thomson, A Blechl - Advances in new technology for targeted …, 2015 - Springer
Here we review multiple uses of site-specific recombination and their applications in plant
genomic engineering. We also outline various strategies for the combined use of multiple …

Determining the Role of Tubulointerstitial Nephritis Antigen-like 1 in Renal Ischemic Reperfusion Injury

PD Pang - 2018 - search.proquest.com
Acute kidney injury (AKI) is a broad term that applies to a wide range of pathological
etiologies characterized by a sudden increase in serum creatinine, a hallmark of …