Therapeutic potential of targeting the receptor for advanced glycation end products (RAGE) by small molecule inhibitors

H Singh, DK Agrawal - Drug development research, 2022 - Wiley Online Library
Receptor for advanced glycation end products (RAGE) is a 45 kDa transmembrane receptor
of immunoglobulin family that can bind to various endogenous and exogenous ligands and …

[HTML][HTML] Astrocytic Alterations and Dysfunction in Down Syndrome: Focus on Neurogenesis, Synaptogenesis, and Neural Circuits Formation

B Uguagliati, M Grilli - Cells, 2024 - mdpi.com
Down syndrome (DS) is characterized by severe neurodevelopmental alterations that
ultimately lead to the typical hallmark of DS: intellectual disability. In the DS brain, since the …