Major Depressive Disorder (MDD) is a prevalent, chronic, disabling, and multidimensional
mental disorder. Cognitive dysfunction represents a core diagnostic and symptomatic …

Cognitive impairments are now widely acknowledged as an important aspect of major
depressive disorder (MDD), and it has been proposed that executive function (EF) may be …

A promising new treatment approach for major depressive disorder (MDD) targets the
microbiota-gut-brain (MGB) axis, which is linked to physiological and behavioral functions …

BACKGROUND: Recurrent-episode Major Depressive Disorder (MDD) is associated with a
number of neuropsychological deficits. To date, less is known about whether these are …

We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

After a pause of nearly 40 years in research into the effects of psychedelic drugs, recent
advances in our understanding of the neurobiology of psychedelics, such as lysergic acid …

Cognitive abnormalities are a core feature of depression, and biases toward negatively
toned emotional information are common, but are they a cause or a consequence of …

Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric
disorders. However, the exact mechanism of action and why effects can take several weeks …

BackgroundWhen challenged with information about the future, healthy participants show an
optimistically biased updating pattern, taking desirable information more into account than …

Depression is a complex and heterogeneous disorder whose cause is poorly understood.
Theories on the mechanisms of the disease have often focused on either its neurobiology or …