The detailed examination of enzyme molecules by mass spectrometry and other techniques
continues to identify hundreds of distinct PTMs. Recently, global analyses of enzymes using …

Enzymes of the UDP-glucuronosyltransferase (UGT) superfamily contribute to the
elimination of drugs from almost all therapeutic classes. Awareness of the importance of …

Long‐chain acyl‐coenzyme A (CoA) synthetase 3 (ACSL 3) is an androgen‐responsive
gene involved in the generation of fatty acyl‐CoA esters. ACSL 3 is expressed in both …

UDP-glucuronosyltransferases (UGTs) are important phase II metabolic enzymes
responsible for approximately 40-70% of endo and xenobiotic reactions. It catalyzes the …

Over the past decade, molecular dynamics (MD) simulations have become particularly
powerful to rationalize drug insertion and partitioning in lipid bilayers. MD simulations …

ETHNOPHARMACOLOGICAL RELEVANCE: The integrated effects of herbal medicines
were the outcome of all of the inherent components. Currently, few studies have focused on …

Uridine diphosphate-glucuronosyltransferases (UGTs) are phase 2 conjugation enzymes
mainly located in the endoplasmic reticulum (ER) of the liver and many other tissues, and …

Tea tree oil (TTO) is a pure natural plant essential oil. The studies evaluated the
hepatopancreas lipid metabolism and antioxidant efficacy of Macrobrachium rosenbergii fed …

Nucleotide sugar-dependent glycosyltransferases (UGTs) are critical to the homeostasis of
endogenous metabolites and the detoxification of xenobiotics. Their impact on the cell …

Background: UDP-glucuronosyltransferases (UGTs) are a class of important phase II drug
metabolizing enzymes (DMEs), playing essential roles in the homeostasis of endobiotics as …